APOB Protein
Quick Overview for APOB Protein (ABIN934464)
Target
See all APOB ProteinsProtein Type
Origin
Source
Purity
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Characteristics
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Purified native Human ApoB protein
Contaminants: Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Protein Source: Human plasma
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Buffer
- Essentially free of other plasma lipoproteins as determined by electrophoresis using Fat Red 7 B stain for lipids and Coomassie Blue for proteins.
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Handling Advice
- Do not freeze.
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Storage
- 4 °C
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Storage Comment
- Store at 2-4 °C.
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- APOB (Apolipoprotein B (APOB))
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Alternative Name
- ApoB
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Background
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Apolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90 mg per 100 ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids out of cells and direct lipids to target organs. Apo B levels are positively correlated with the risk of coronary disease. Apo B levels may be a more sensitive predictor of cardiovascular risk than LDL levels and do not involve fasting for accurate measurement. Two forms of Apo B exist: Apo B-100 and Apo B-48. The first is found in VLDL and LDL and is produced by the liver. The second is found in chylomicrons and originates in the intestine. .
Description: Human plasma.
Alternative Names: Apolipoprotein B protein, Apo-B protein, Apo B protein, Low Density lipoprotein protein, LDL protein -
Molecular Weight
- 550 kDa
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Pathways
- Lipid Metabolism
Target
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