C-Peptide Protein (full length)

Catalog No. ABIN934540

Synthetic C-Peptide protein expressed in Human.

Quick Overview for C-Peptide Protein (full length) (ABIN934540)

Target: C-Peptide

Protein Type: Synthetic

Origin: Human

Source: Human

Purity: > 98 % pure

Product Details

Protein Characteristics: full length

Sequence: Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg

Characteristics: Purified recombinant Human C Peptide protein
Protein Source: Human (full length synthetic C-peptide) Tyr-C-Peptide

Purification: purified

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder purified by HPLC, tyrosine residue.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details

Target: C-Peptide

Alternative Name: C Peptide

Background: Proinsulin C-peptide was first described in 1967 in connection with the discovery of the insulin biosynthesis. It serves as an important linker between the A- and the B- chains of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are then stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. Initially, the sole interest in C-peptide was as a marker of insulin secretion and has as such been of great value in furthering the understanding of the pathophysiology of type 1 and type 2 diabetes. The first documented use of the C-peptide test was in 1972. During the past decade, however, C-peptide has been found to be a bioactive peptide in its own right, with effects on microvascular blood flow and tissue health.
Description: Human (full length synthetic C-peptide) Tyr-C-Peptide.
Alternative Names: Proinsulin connecting peptide, C-Peptide protein

Molecular Weight: 3616.99 kDa