Troponin I Protein (TNNI)

Catalog No. ABIN934731

This Recombinant Troponin I protein is expressed in Escherichia coli (E. coli) and has been mentioned in 1 publication.

Quick Overview for Troponin I Protein (TNNI) (ABIN934731)

Target: Troponin I (TNNI)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Characteristics: Purified Recombinant Human Troponin I protein (Cardiac)
Expression System: E.coli

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Buffer: Supplied in 6 M Urea, 56 M Tris, pH 8.0

Precaution of Use: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Aliquot and store at -25 °C.

References

Mulvaney, Cole, Kniller, Malito, Tamanaha, Rife, Stanton, Whitman: "Rapid, femtomolar bioassays in complex matrices combining microfluidics and magnetoelectronics." in: Biosensors & bioelectronics, Vol. 23, Issue 2, pp. 191-200, (2007) (PubMed).

Target Details

Target: Troponin I (TNNI)

Alternative Name: Troponin I

Background: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
Description: E.coli.

Molecular Weight: 24 kDa