IL-8 Protein

Catalog No. ABIN934922

Product Details

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MAVLPRSAKE LRCQCIKTYS KPFHPKFIKE LRVIESGPHC ANTEIIVKLS DGRELCLDPK ENWVQRVVEK FLKRAENS

Characteristics: Purified recombinant Human IL8 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Purity: > 95 % pure

Endotoxin Level: < 1.0 EU per µg of protein (determined by LAL method)

Application Details

Application Notes: IL8 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in PBS, pH 7.4.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: IL8 (IL8 Products)

Background: Interleukin-8 (IL-8) is a chemokine, a member of the cytokine family that displays chemotactic activity for specific types of leukocytes. It is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8/IL-8 in response to a wide variety of pro-inflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses. Recombinant human IL-8 was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: GCP1 protein, Granulocyte chemotactic protein 1 protein, LYNAP protein, 310C protein, Inteleukin 8 protein, , AMCF 1 protein, IL-8 protein, TCF protein, NAP1 protein, IL 8 protein, T-lymphocyte chemotactic factor protein, Neurophil chemotactic factor protein, CXCL8 protein, Emoctakin protein, Granulocyte chemotactic protein protein, Neutrophil activating protein protein, SCYB8 protein, Protein 3 10C protein, LECT protein, TSG 1 protein, b ENAP protein, Neutrophil activating protein 1 protein, Interleukin8 protein, NAP protein, NAF protein, SCYB 8 protein, IL8, and Leukocyte adhension inhibitor protein, MDNCF a protein, Monocyte derived neutrophil activating protein protein, Beta thromboglobulin like protein protein, LAI protein, IL-8, NAP 1 protein, 3 10C protein, GCP 1 protein, NCF protein, K 60 protein, TSG1 protein, Lymphocyte derived neutrophil activating factor protein, CXCL 8 protein, T cell chemotactic factor protein, GCP protein, MDNCF protein, Monocyte derived neutrophil chemotactic factor protein, IL 8 protein, MDNCF alpha protein, MDNCF protein, AMCF1 protein, CXC chemokine ligand 8 protein, Monocyte derived neutrophil chemotactic factor protein, MONAP protein, IL 8, LUCT protein, Neutrophil activating factor protein

Molecular Weight: 9 kDa (78 AA)

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy