IL-8 Protein (AA 28-99)
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- Target See all IL-8 (IL8) Proteins
- IL-8 (IL8) (Interleukin 8 (IL8))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 28-99
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Cell Migration Assay (CMA)
- Sequence
- SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
- Characteristics
- Recombinant Human CXCL8 (IL-8)
- Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.083 nM determined by Migration Assay in cells expressing recombinant CXCR1
- Top Product
- Discover our top product IL8 Protein
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Interleukin 8 (IL8) (AA 28-99) protein (His tag)
IL8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 8 (IL8) (AA 28-99) (Active) protein (His tag,AVI tag,Biotin)IL8 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 8 (IL8) (AA 26-167) protein (His-IF2DI Tag)IL8 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 8 (IL8) (AA 21-99) protein (GST tag)IL8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 8 (IL8) (AA 1-99) protein (GST tag)IL8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 8 (IL8) (AA 28-99) protein (Fc Tag)IL8 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Interleukin 8 (IL8) (AA 23-99) protein (His tag)Crystallography grade IL8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 8 (IL8) (AA 21-99) protein (His tag)Crystallography grade IL8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 8 (IL8) (AA 27-99) protein (His tag)Crystallography grade IL8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 8 (IL8) (AA 29-99) protein (His tag)Crystallography grade IL8 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Storage
- -20 °C,-80 °C
- Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Expiry Date
- 12 months
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- Target
- IL-8 (IL8) (Interleukin 8 (IL8))
- Alternative Name
- CXCL8 (IL-8) (IL8 Products)
- Synonyms
- CXCL8 Protein, GCP-1 Protein, GCP1 Protein, LECT Protein, LUCT Protein, LYNAP Protein, MDNCF Protein, MONAP Protein, NAF Protein, NAP-1 Protein, NAP1 Protein, IL-8 Protein, AMCF-I Protein, il8 Protein, IL8 Protein, si:dkey-151b16.2 Protein, cxcli2 Protein, cxcl8 Protein, gcp-1 Protein, il-8 Protein, lynap Protein, mdncf Protein, monap Protein, nap-1 Protein, C-X-C motif chemokine ligand 8 Protein, interleukin 8 Protein, chemokine (C-X-C motif) ligand 8a Protein, chemokine (C-X-C motif) ligand 1-like Protein, chemokine (C-X-C motif) ligand 8 L homeolog Protein, CXCL8 Protein, il8 Protein, cxcl8a Protein, IL8 Protein, Cxcl8 Protein, LOC422654 Protein, cxcl8.L Protein
- Background
- Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.
- Molecular Weight
- 8.386 kDa
- UniProt
- P10145
- Pathways
- TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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