Nanog Protein (AA 1-305)
Quick Overview for Nanog Protein (AA 1-305) (ABIN935111)
Target
See all Nanog (NANOG) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-305
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Sequence
- MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA EKSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDV
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Characteristics
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Purified recombinant Nanog protein
Expression System: E.coli
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Nanog Homeobox (NANOG) (AA 1-305) protein (His tag)
custom-made NANOG Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nanog Homeobox (NANOG) (AA 1-305) protein (His tag)custom-made NANOG Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nanog Homeobox (NANOG) (AA 2-305) protein (His tag)NANOG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nanog Homeobox (NANOG) (AA 1-305) proteinNANOG Origin: Human Host: Escherichia coli (E. coli) > 90 % by SDS - PAGE SDS
Nanog Homeobox (NANOG) (AA 1-154) protein (His tag)NANOG Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
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Application Notes
- Nanog protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0.4 M Urea and 5 % glycerol.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Alternative Name
- Nanog
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Background
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Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
Alternative Names: Homeobox transcription factor Nanog protein, homeobox transcription factor Nanog-delta 48 protein -
Molecular Weight
- 34.6 kDa (305 AA)
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Pathways
- Stem Cell Maintenance
Target
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