TNFRSF13C Protein
Quick Overview for TNFRSF13C Protein (ABIN935243)
Target
See all TNFRSF13C ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
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Characteristics
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Purified recombinant Human BAFF Receptor protein
Expression System: E.coli
Bioactivity: Determined by its ability to bl °Ck BAFF induced mouse splen °Cyte survival. The expected ED50 for this effect is 2.0-4.0 µg/mL in the presence of 1.0µg/mL of human soluble BAFF. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg)
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Alternative Name
- BAFF Receptor
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Background
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BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation.
Alternative Names: BAFFR protein, TNFRSF13C protein -
Molecular Weight
- 7.7 kDa
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Pathways
- NF-kappaB Signaling
Target
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