Collagen IV Protein

Catalog No. ABIN935267

This Native Collagen IV protein is produced in Human.

Quick Overview for Collagen IV Protein (ABIN935267)

Target: Collagen IV (COL4) (Collagen, Type IV (COL4))

Protein Type: Native

Origin: Human

Source: Human

Product Details

Characteristics: Purified native Human Collagen Type IV protein
Protein Source: Human placenta

Purification: Affinity chromatography

Sterility: Sterile filtered

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Sterile filtered liquid in 0.5 M CH3COOH, with 0.01 % NaN3.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Dilute only prior to immediate use.

Storage: 4 °C

Target Details

Target: Collagen IV (COL4) (Collagen, Type IV (COL4))

Alternative Name: Collagen Type IV

Background: Collagen IV is a major constituent of the basement membranes along with laminins, proteoglycans and enactins. It is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. It can form insoluble fibers with high tensile strength. Collagen IV is useful in detecting the loss of parts of basement membranes in carcinomas.
Description: Human placenta.
Alternative Names: Canstatin protein, Arresten protein, Collagen Of Basement Membrane alpha 1 Chain protein