Cytokeratin 18 Protein

Catalog No. ABIN935277

This Recombinant Cytokeratin 18 protein is expressed in Escherichia coli (E. coli).

Quick Overview for Cytokeratin 18 Protein (ABIN935277)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Control Peptide (CP)

Product Details

Characteristics: Purified recombinant Human Cytokeratin 18 protein
Expression System: E.coli

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Comment:

Protein standard in 1D and 2D SDS gel electrophoresis, Immunoassays, Immunization

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 175 μL distilled water (final volume 250 μL)

Buffer: Lyophilized from solution containing 30 mM Tris/HCI pH 8, 9.5 M urea, 2 mM DTT, 2 mM EDTA, and 10 mM methylammonium chloride.

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: Cytokeratin 18

Background: Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Alternative Names: Cytokeratin 18 protein, Cytokeratin 18, Cytokeratin-18 protein, Cytokeratin-18, Keratin K18 protein, Cytokeratin 18

Molecular Weight: 45 kDa

Pathways: Apoptosis, Caspase Cascade in Apoptosis