C12orf57 Protein

Catalog No. ABIN935298

This Recombinant C12orf57 protein is expressed in Escherichia coli (E. coli).

Quick Overview for C12orf57 Protein (ABIN935298)

Target: C12orf57 (Chromosome 12 Open Reading Frame 57 (C12orf57))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA

Characteristics: Purified recombinant Mouse C10 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10.0-100.0 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: C12orf57 (Chromosome 12 Open Reading Frame 57 (C12orf57))

Alternative Name: C10

Background: Mouse C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL3 or IL4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues.
Alternative Names: C-10, MRP-1 protein, C10, C-10 protein, C 10, CCL6 protein, C 10 protein, C-10 protein

Molecular Weight: 10.7 kDa