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G-CSF Protein

CSF3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935376
  • Target See all G-CSF (CSF3) Proteins
    G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 23
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 22
    • 10
    • 5
    • 3
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
    Characteristics
    Purified recombinant Human GCSF protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse M-NFS-60 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product CSF3 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 5 mM sodium citrate, pH 4.0.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
  • Target
    G-CSF (CSF3) (Colony Stimulating Factor 3 (Granulocyte) (CSF3))
    Alternative Name
    GCSF (CSF3 Products)
    Background
    G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and Mouse G-CSF are cross-species reactive.
    Alternative Names: CSF-3 protein, Granulocyte Colony-Stimulating Factor protein, GM-CSF beta protein, MGI-1G protein, pluripoietin protein
    Molecular Weight
    18.7 kDa
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
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