ILGFBP1 (full length) (Active) Protein
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
-
- Target
- ILGFBP1
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- full length
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Characteristics
-
Purified recombinant Human ILGFBP1 protein
Expression System: E.coli
Bioactivity: Inhibition of IGF-I stimulated proliferation of NUC-1 cells: IC50 ~ 100 ng/mL Inhibition of serum-induced stimulation of DNA synthesis in chick embryo fibroblast primary cultures: IC50 (1 % serum) ~300 ng/mL. - Purity
- > 98 % pure
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute in 20 mM CH3COOH at the stock concentration of not less than 0.1 mg/mL.
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
-
- Target
- ILGFBP1
- Background
-
IGFBP1 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alternative Names: ILGFBP-1, hIGFBP-1 protein, PP12 protein, ILGFBP1, ILGFBP 1, ILGFBP-1 protein, ILGFBP-1 protein, AFBP protein, ILGFBP 1 protein, IGF-BP25 protein, IGF-Binding Protein 1 protein, IBP-1 protein, IGFBP-1 protein, Insulin Like Growth Factor Binding Protein 1 protein - Molecular Weight
- 25.3 kDa
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