TNFSF14 Protein
Quick Overview for TNFSF14 Protein (ABIN935618)
Target
See all TNFSF14 ProteinsProtein Type
Origin
Source
Purity
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Sequence
- MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
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Characteristics
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Purified recombinant Human LIGHT protein
Expression System: E.coli -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 89-240), (Trimer) protein (His-DYKDDDDK Tag)
TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) protein (His tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) protein (Fc Tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) protein (Fc Tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239) protein (His tag)custom-made TNFSF14 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-240) protein (His tag)custom-made TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 89-240) protein (His-DYKDDDDK-Strep II Tag)TNFSF14 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) (Active) protein (His tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 71-240) protein (His-IF2DI Tag)TNFSF14 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-177) protein (GST tag)TNFSF14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
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Background
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LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.
Alternative Names: TNFSF14 protein, HVEM-L protein, TNF14 protein, Ligand for herpesvirus entry mediator protein, CD258 protein -
Molecular Weight
- 20.1 kDa
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Pathways
- Cancer Immune Checkpoints
Target
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