Resistin Protein (RETN)
Quick Overview for Resistin Protein (RETN) (ABIN935760)
Target
See all Resistin (RETN) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- SSKTLCSMEE AINERIQEVA GSLIFRAISS IGLECQSVTS RGDLATCPRG FAVTGCTCGS ACGSWDVRAE TTCHCQCAGM DWTGARCCRV QP
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Characteristics
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Purified recombinant Human Resistin protein
Expression System: E.coli
Bioactivity: Determined by its ability to stimulate lipolysis in cultured human adipocytes. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Resistin (RETN) (Active) protein
RETN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Resistin (RETN) (AA 17-108) protein (Fc Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 21-114) protein (Fc Tag)RETN Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Resistin (RETN) (AA 16-108) protein (His tag)RETN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Resistin (RETN) (AA 1-108) protein (GST tag)RETN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Resistin (RETN) (AA 19-108) protein (Fc Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Resistin (RETN) protein (Myc-DYKDDDDK Tag)RETN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Supplied lyophilized with no additives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Resistin (RETN)
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Alternative Name
- Resistin
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Background
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Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-a and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes.
Alternative Names: Adipose tissue-specific secretory factor protein, FIZZ3 protein, ADSF protein -
Molecular Weight
- 19.5 kDa
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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