TIFF3 (Active) Protein
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
-
- Target
- TIFF3
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Sequence
- EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF
- Characteristics
-
Purified recombinant Human TIFF3 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1.0-10.0 µg/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
-
- Target
- TIFF3
- Background
-
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.
Alternative Names: TIFF-3 protein, TIFF 3, Intestinal trefoil factor protein, TIFF-3, Trefoil Factor 3 protein, ITF protein, TIFF-3 protein, TFI protein, TIFF 3 protein, TIFF3 - Molecular Weight
- 13.2 kDa
-
You are here:
