C3 Protein
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- Target See all C3 Proteins
- C3 (Complement Component 3 (C3))
- Protein Type
- Native
- Biological Activity
- Active
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Origin
- Human
- Host
- Please inquire
- Characteristics
- Bioactivity: 13,200 units/mg.
- Purity
- > 98 % pure by SDS PAGE
- Top Product
- Discover our top product C3 Protein
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- Restrictions
- For Research Use only
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- Storage
- -80 °C
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- Target
- C3 (Complement Component 3 (C3))
- Alternative Name
- Complement C3 (C3 Products)
- Background
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Native human C3 is a naturally glycosylated polypeptide containing two disulfide-linked chains. C3 is central to the activation of all three pathways of complement activation. Initiation of each pathway generates proteolytic enzyme complexes (C3 convertases) which are bound to the target surface. These enzymes cleave a peptide bond in C3 releasing the anaphylatoxin C3a and activating C3b. For a brief time (~60 us) this nascent C3b is capable of reacting with and covalently coupling to hydroxyl groups on the target surface.
Description: Human serum/plasma. Synonyms: C3 protein. - Pathways
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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