IL-33 Protein
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- Target See all IL-33 (IL33) Proteins
- IL-33 (IL33) (Interleukin 33 (IL33))
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Sequence
- SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSK
- Characteristics
- Fully biologically active when compared to standard. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106units/mg.
- Purity
- > 98 % by SDS-PAGE and HPLC analyses.
- Endotoxin Level
- Level Less than 1EU/µg of rMuIL-33 as determined by LAL method
- Top Product
- Discover our top product IL33 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
- Storage
- 4 °C
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- Target
- IL-33 (IL33) (Interleukin 33 (IL33))
- Alternative Name
- Interleukin-33 (IL-33) (IL33 Products)
- Background
- IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Synonym: Interleukin-33 (IL-33), Mouse. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, EDTA and DTT, pH 7.4.
- Molecular Weight
- Approximately 17.5 kDa protein containing 158 amino acid residues.
- Pathways
- Production of Molecular Mediator of Immune Response
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