Browse our anti-HVCN1 (HVCN1) Antibodies

Full name:: anti-Hydrogen Voltage-Gated Channel 1 Antibodies (HVCN1)

On www.antibodies-online.com are 46 Hydrogen Voltage-Gated Channel 1 (HVCN1) Antibodies from 0 different suppliers available. A total of 58 HVCN1 products are currently listed.

Synonyms:: 0610039P13Rik, AI450555, BTS, HV1, HVCN1, mVSOP, RGD1310788, Vsop, vsx1, zgc:92181

list all antibodies	Gene Name	GeneID	UniProt
Anti-Human HVCN1	HVCN1	84329	Q96D96
Anti-Mouse HVCN1	HVCN1	74096	Q3U2S8
Anti-Rat HVCN1	HVCN1	304485
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Relevant Pathways for anti-HVCN1 Antibodies

Proton Transport

More product categories related to HVCN1 Antibody

More Antibodies against HVCN1 Interaction Partners

Human Hydrogen Voltage-Gated Channel 1 (HVCN1) interaction partners

The authors now report that R1H mutation is sufficient to reconstitute resting-state H(+) 'shuttle' conductance in Hv1 without abrogating the intrinsic 'aqueous' H(+) conductance.
We suggest that cleavage and heterodimerization of Hv1 represents an adaptation to the specific requirements of pH control in sperm.
Inhibition of Hv1 channels by Zn(2+).
CREBBP (show CREBBP Antibodies) mutations were associated with inferior progression-free survival (PFS), whereas mutations in previously unreported HVCN1, a voltage-gated proton channel-encoding gene and B-cell receptor signaling modulator, were associated with improved PFS.
Our data demonstrated that the expression of Hv1 in pancreatic islet beta-cells regulates insulin (show INS Antibodies) secretion through regulating Ca(2 (show CA2 Antibodies)+) homeostasis.
The main properties of the voltage-gated proton channel (HV1) are described in this review, along with what is known about how the channel protein structure accomplishes its functions. [review]
Hv1 activity displays hysteresis
A shorter isoform of HVCN1 with enhanced gating is specifically enriched in malignant B cells.
Divalent metal binding causes a conformational change in human the Hv1 c-terminal domain.
analysis of of the C-terminal domain of voltage-gated proton channel HV1 and the thermodynamic characteristics of Zn(2) binding to this domain

Mouse (Murine) Hydrogen Voltage-Gated Channel 1 (HVCN1) interaction partners

loss of Hv1 significantly attenuates STZ-induced beta-cell damage and ROS (show ROS1 Antibodies) production in pancreatic beta-cells; results suggest that Hv1 might contribute to development of diabetes through producing ROS (show ROS1 Antibodies).
Hv1 channels therefore differentially regulate the pHp (show FXYD6 Antibodies) in neutrophils and macrophages, sustaining rapid acidification in macrophage phagosomes and maintaining a neutral pH in neutrophil phagosomes.
microglial Hv1 proton channel is a unique target for modulation of microglial M1/M2 polarization in the pathogenesis of ischemic stroke
Alkalinity of neutrophil phagocytic vacuoles is modulated by HVCN1.
The voltage-gated proton channel Hv1/VSOP inhibits neutrophil granule release
Our data demonstrated that the expression of Hv1 in pancreatic islet beta-cells regulates insulin (show INS Antibodies) secretion through regulating Ca(2 (show CA2 Antibodies)+) homeostasis.
Eosinophils require proton channel HVCN1 for optimal reactive oxygen species generation and prevention of activation-induced cell death.
Functional expression of voltage-gated proton (Hv1) channels is characterized, for the first time, in mouse bone marrow-derived dendritic cells.
inhibition of Hv1 function via knockdown of Hv1 expression can effectively retard cancer growth
Hv1 channels maintain a physiological membrane potential during the respiratory burst of neutrophils by providing a compensating charge for the electrons transferred by NOX2 from NADPH to superoxide.

HVCN1 Antigen Profile

Antigen Summary

This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with HVCN1

hydrogen voltage-gated channel 1 (hvcn1) antibody
hydrogen voltage gated channel 1 pseudogene (LOC452241) antibody
hydrogen voltage gated channel 1 (hvcn1) antibody
hydrogen voltage gated channel 1 (HVCN1) antibody
voltage-gated hydrogen channel 1 (hvcn1) antibody
hydrogen voltage-gated channel 1 (Hvcn1) antibody
hydrogen voltage gated channel 1 L homeolog (hvcn1.L) antibody

0610039P13Rik antibody
AI450555 antibody
BTS antibody
HV1 antibody
HVCN1 antibody
mVSOP antibody
RGD1310788 antibody
Vsop antibody
vsx1 antibody
zgc:92181 antibody

Protein level used designations for HVCN1

HV1 , voltage-gated hydrogen channel 1 , hydrogen voltage-gated channel 1 , voltage sensor domain-only protein

GENE ID	SPECIES
436618	Danio rerio
452241	Pan troglodytes
496712	Xenopus (Silurana) tropicalis
608547	Canis lupus familiaris
616570	Bos taurus
778897	Ciona intestinalis
100152115	Sus scrofa
84329	Homo sapiens
74096	Mus musculus
416871	Gallus gallus
304485	Rattus norvegicus
496219	Xenopus laevis

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