HVCN1 antibody (C-Term)
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- Target See all HVCN1 Antibodies
- HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HVCN1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- HVCN1 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- HVCN1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human HVCN1. The immunogen is located within the last 50 amino acids of HVCN1.
- Isotype
- IgG
- Top Product
- Discover our top product HVCN1 Primary Antibody
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- Application Notes
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HVCN1 antibody can be used for detection of HVCN1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- HVCN1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- HVCN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- HVCN1 (Hydrogen Voltage-Gated Channel 1 (HVCN1))
- Alternative Name
- HVCN1 (HVCN1 Products)
- Synonyms
- zgc:92181 antibody, HVCN1 antibody, VSOP antibody, vsx1 antibody, HV1 antibody, 0610039P13Rik antibody, AI450555 antibody, BTS antibody, Vsop antibody, mVSOP antibody, RGD1310788 antibody, hydrogen voltage-gated channel 1 antibody, hydrogen voltage gated channel 1 pseudogene antibody, hydrogen voltage gated channel 1 antibody, voltage-gated hydrogen channel 1 antibody, hydrogen voltage gated channel 1 L homeolog antibody, hvcn1 antibody, LOC452241 antibody, HVCN1 antibody, Hvcn1 antibody, hvcn1.L antibody
- Background
- HVCN1 Antibody: HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.
- Molecular Weight
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Predicted: 30 kDa
Observed: 30 kDa - Gene ID
- 84329
- NCBI Accession
- NP_115745
- UniProt
- Q96D96
- Pathways
- Proton Transport
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