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PYGM Products

(Phosphorylase, Glycogen, Muscle (PYGM))
This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009].

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Featured PYGM Categories

PYGM Antibodies

High quality antibodies with extensive validation data.

PYGM ELISA Kits

Reliable ELISA kits for a wide range of species.

PYGM Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PYGM Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (5)
Cat. No. ABIN519574
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN952549
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7130796
Quantity 100 μL
Datasheet Datasheet

Recommended PYGM ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969318
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969320
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969319
Quantity 96 tests
Datasheet Datasheet

Recommended PYGM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094849
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3137508
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316982
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PYGM products

Bheemanapally, Ibrahim, Briski: "Combinatory high-resolution microdissection/ultra performance liquid chromatographic-mass spectrometry approach for small tissue volume analysis of rat brain glycogen." in: Journal of pharmaceutical and biomedical analysis, Vol. 178, pp. 112884, (2020) (PubMed).

Hasan Mahmood, Mandal, Bheemanapally, Ibrahim, Briski: "Norepinephrine control of ventromedial hypothalamic nucleus glucoregulatory neurotransmitter expression in the female rat: Role of monocarboxylate transporter function." in: Molecular and cellular neurosciences, Vol. 95, pp. 51-58, (2019) (PubMed).

Briski, Mandal: "Hindbrain lactoprivic regulation of hypothalamic neuron transactivation and gluco-regulatory neurotransmitter expression: Impact of antecedent insulin-induced hypoglycemia." in: Neuropeptides, Vol. 77, pp. 101962, (2019) (PubMed).

Hathout, Marathi, Rayavarapu, Zhang, Brown, Seol, Gordish-Dressman, Cirak, Bello, Nagaraju, Partridge, Hoffman, Takeda, Mah, Henricson, McDonald: "Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients." in: Human molecular genetics, Vol. 23, Issue 24, pp. 6458-69, (2015) (PubMed).

de Luna, Brull, Lucia, Santalla, Garatachea, Martí, Andreu, Pinós: "PYGM expression analysis in white blood cells: A complementary tool for diagnosing McArdle disease?" in: Neuromuscular disorders : NMD, (2014) (PubMed).

Parker, Koay, Gilbert-Wilson, Waddington, Stapleton: "AMP-activated protein kinase does not associate with glycogen alpha-particles from rat liver." in: Biochemical and biophysical research communications, Vol. 362, Issue 4, pp. 811-5, (2007) (PubMed).

Tsoi, Cale, Bird, Kay: "cDNA microarray analysis of gene expression profiles in human placenta: up-regulation of the transcript encoding muscle subunit of glycogen phosphorylase in preeclampsia." in: Journal of the Society for Gynecologic Investigation, Vol. 10, Issue 8, pp. 496-502, (2003) (PubMed).

Hertel, Zhou, Hamilton-Dutoit, Junker: "Loss of B cell identity correlates with loss of B cell-specific transcription factors in Hodgkin/Reed-Sternberg cells of classical Hodgkin lymphoma." in: Oncogene, Vol. 21, Issue 32, pp. 4908-20, (2002) (PubMed).

Hadjigeorgiou, Sadeh, Musumeci, Dabby, De Girolami, Naini, Papadimitriou, Shanske, DiMauro: "Molecular genetic study of myophosphorylase deficiency (McArdle's disease) in two Yemenite-Jewish families." in: Neuromuscular disorders : NMD, Vol. 12, Issue 9, pp. 824-7, (2002) (PubMed).

Bruno, Lanzillo, Biedi, Iadicicco, Minetti, Santoro: "Two new mutations in the myophosphorylase gene in Italian patients with McArdle's disease." in: Neuromuscular disorders : NMD, Vol. 12, Issue 5, pp. 498-500, (2002) (PubMed).

Synonyms and alternative names related to PYGM

glycogen phosphorylase, muscle associated (PYGM), glycogen phosphorylase, muscle form (THA_70), muscle glycogen phosphorylase (Pygm), phosphorylase, glycogen, muscle A (pygma), glycogen phosphorylase, muscle associated (Pygm), AI115133, im:7150327, Muscpho, PG, zgc:110706

Protein level used designations for PYGM

  • glycogen phosphorylase
  • glycogen phosphorylase, muscle form
  • phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V)
  • phosphorylase, glycogen. muscle
  • myophosphorylase
  • Phosphorylase glycogen
  • Phosphorylase, glycogen; muscle (McArdle syndrome)
  • muscle (McArdle syndrome)
  • muscle glycogen phosphorylase
  • glycogen myophosphorylase
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