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NMR structure of the C-terminal headpiece subdomains of advillin. Evaluation of F-actin-binding requirements.
Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants.
study highlights a role for advillin in growth cone formation, axon regeneration, and neuropathic pain associated with IB4(+) DRG neurons in adulthood.
interaction of SREC-I (show SCARF1 Proteins) and advillin are involved in the development of dorsal root ganglion neurons by inducing the described morphological changes.
This study found that the regenerative axon growth of Advillin-null sensory neurons is significantly shortened and that deletion of Advillin reduces the plasticity of whisker-related barrelettes patterns in the hindbrain.
The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia.
, actin-binding protein DOC6
, peripheral nervous system villin-like protein