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NMR structure of the C-terminal headpiece subdomains of advillin. Evaluation of F-actin-binding requirements.
Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants.
study highlights a role for advillin in growth cone formation, axon regeneration, and neuropathic pain associated with IB4(+) DRG neurons in adulthood.
interaction of SREC-I and advillin are involved in the development of dorsal root ganglion neurons by inducing the described morphological changes.
This study found that the regenerative axon growth of Advillin-null sensory neurons is significantly shortened and that deletion of Advillin reduces the plasticity of whisker-related barrelettes patterns in the hindbrain.
The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia.
, actin-binding protein DOC6
, peripheral nervous system villin-like protein