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anti-TXK tyrosine Kinase Antibodies

45 TXK tyrosine Kinase (TXK) Antibodies from 13 manufacturers are available on www.antibodies-online.com.

45 results:

anti-TXK tyrosine Kinase (TXK) (AA 22-52), (N-Term) antibody Primary Antibody

TXK Reactivity: Human IHC (p), WB Host: Rabbit Polyclonal RB03245 unconjugated
Catalog No. ABIN392114
$412.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-TXK tyrosine Kinase (TXK) (C-Term) antibody Primary Antibody

TXK Reactivity: Human ELISA, IHC, WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN570663
$481.84
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 6 to 7 Business Days

anti-TXK tyrosine Kinase (TXK) (AA 286-509) antibody Primary Antibody

TXK Reactivity: Mouse ICC, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1860890
$252.00
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 13 Business Days

anti-TXK tyrosine Kinase (TXK) (AA 131-230) antibody Primary Antibody

TXK Reactivity: Human IF, ELISA, WB Host: Mouse Monoclonal 2D8 unconjugated
Catalog No. ABIN521176
$440.00
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-TXK tyrosine Kinase (TXK) antibody Primary Antibody

TXK Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3222974
$487.50
Plus shipping costs $45.00
200 μL
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-TXK tyrosine Kinase (TXK) (N-Term) antibody Primary Antibody

TXK Reactivity: Human EIA, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359999
$539.00
Plus shipping costs $45.00
0.4 mL
local_shipping Shipping to: United States
Delivery in 6 to 8 Business Days

anti-TXK tyrosine Kinase (TXK) (AA 321-366) antibody Primary Antibody

TXK Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6711048
$350.00
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 6 to 11 Business Days

anti-TXK tyrosine Kinase (TXK) antibody Primary Antibody

TXK Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265813
$390.77
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 8 to 9 Business Days

anti-TXK tyrosine Kinase (TXK) (Internal Region) antibody Primary Antibody

TXK Reactivity: Human ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6287143
$318.71
Plus shipping costs $45.00
50 μL
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-TXK tyrosine Kinase (TXK) antibody Primary Antibody

TXK Reactivity: Human IF, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2154106
$481.61
Plus shipping costs $45.00
50 μL
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days
  • Type Primary
    • Primary
  • Target TXK tyrosine Kinase (TXK)
    • TXK tyrosine Kinase (TXK)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Albumin (ALB)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-KB P65 (NFkBP65)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Tuberous Sclerosis 2 (TSC2)
    • CD8a Molecule (CD8A)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD19 Molecule (CD19)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Integrin alpha M (ITGAM)
    • CD8
    • Hemagglutinin (HA)
    • Histone H4
    • CD44
    • Interleukin 6 (IL6)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Myc Proto-Oncogene protein (MYC)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Jun Proto-Oncogene (JUN)
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD5 Molecule (CD5)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD3
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Vimentin (VIM)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • CD14
    • Interleukin 2 (IL2)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD34
    • alpha-Fetoprotein (AFP)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • Keratin 18 (KRT18)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Enzyme Immunoassay (EIA)
    • Flow Cytometry (FACS)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Images available
  • Host
    • Rabbit
    • Goat
    • Mouse
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • 1H5
    • 2D8
    • RB03245
  • Binding Specificity
    • N-Term
    • AA 22-52
    • C-Term
    • AA 32-83
    • AA 131-230
    • AA 286-509
    • AA 321-366
    • Center
    • Internal Region
    • Middle Region
  • Conjugate
    • Un-conjugated
    • Biotin
    • FITC
    • HRP
    • APC
    • Alkaline Phosphatase (AP)
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
  • Isotype
    • IgG
    • Ig Fraction
    • IgG2a kappa
    • IgG3 kappa
  • Format
    • Liquid

TXK tyrosine Kinase (TXK) Antigen Profile

Protein Summary

Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T- cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420. Phosphorylation leads to TXK full activation. Contributes also to signaling from many receptors and participates in multiple downstream pathways, including regulation of the actin cytoskekleton. Like ITK, can phosphorylate PLCG1, leading to its localization in lipid rafts and activation, followed by subsequent cleavage of its substrates. In turn, the endoplasmic reticulum releases calcium in the cytoplasm and the nuclear activator of activated T-cells (NFAT) translocates into the nucleus to perform its transcriptional duty. With PARP1 and EEF1A1, TXK forms a complex that acts as a T-helper 1 (Th1) cell- specific transcription factor and binds the promoter of IFNG to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. Phosphorylates both PARP1 and EEF1A1. Phosphorylates also key sites in LCP2 leading to the up-regulation of Th1 preferred cytokine IL-2. Phosphorylates 'Tyr- 201' of CTLA4 which leads to the association of PI-3 kinase with the CTLA4 receptor.

Alternative names and synonyms associated with TXK tyrosine Kinase (TXK)

  • TXK tyrosine kinase (TXK) antibody
  • TXK tyrosine kinase (Txk) antibody
  • tyrosine-protein kinase TXK (LOC100544958) antibody
  • A130089B16Rik antibody
  • Btkl antibody
  • PSCTK5 antibody
  • PTK4 antibody
  • Rlk antibody
  • TKL antibody

Protein level used designations for TXK

PTK4 protein tyrosine kinase 4 , protein-tyrosine kinase 4 , resting lymphocyte kinase , tyrosine kinase , tyrosine-protein kinase TXK , PTK-RL-18 , TXK tyrosine kinase , tyrosine-protein kinase TXK-like , LOW QUALITY PROTEIN: tyrosine-protein kinase TXK

GENE ID SPECIES
7294 Homo sapiens
22165 Mus musculus
305311 Rattus norvegicus
444993 Sus scrofa
461344 Pan troglodytes
482139 Canis lupus familiaris
504782 Bos taurus
705104 Macaca mulatta
770387 Gallus gallus
100019276 Monodelphis domestica
100054343 Equus caballus
100341671 Oryctolagus cuniculus
100397226 Callithrix jacchus
100455862 Pongo abelii
100464564 Ailuropoda melanoleuca
100544958 Meleagris gallopavo
100598060 Nomascus leucogenys
100722451 Cavia porcellus

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