anti-TXK tyrosine Kinase Antibodies

61 TXK tyrosine Kinase (TXK) Antibodies from 16 manufacturers are available on www.antibodies-online.com.

Data Quality
  • 1
  • 13
Type
  • 61
    Primary antibodies
Antigen
  • 61
Reactivity
  • 57
  • 6
  • 5
Application
  • 42
  • 41
  • 29
  • 5
  • 4
Detection Method
  • 3
Host
  • 46
  • 8
  • 7
Clonality
  • 53
  • 8
Clone
  • 3
  • 1
  • 1
  • 1
  • 1
Binding Specificity
  • 9
  • 8
  • 7
  • 7
  • 4
Conjugate
  • 33
  • 5
  • 4
  • 4
  • 3
Isotype
  • 32
  • 6
  • 1
  • 1
  • 1
Format
  • 45
61 Products
ReactivityHuman
Application ELISA, IHC, WB
Order details Cat. No. ABIN570663
$429.87
100 μg
Plus shipping costs $45.00
Delivery in 6 to 7 Business Days
ReactivityHuman
Application IHC (p), ELISA, WB
Order details Cat. No. ABIN544400
$431.43
400 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
Mouse, Monoclonal (2D8), IgG2a kappa
ReactivityHuman
Application IF, ELISA, WB
Order details Cat. No. ABIN521176
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityMouse (Murine)
Application IF/ICC, IHC, IP, WB
Order details Cat. No. ABIN2904467
$450.23
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN3003457
$590.93
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN3222974
$487.50
200 μL
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
Rabbit, Polyclonal, Ig Fraction
ReactivityHuman
Application EIA, IHC (p), WB
Order details Cat. No. ABIN359999
$522.50
0.4 mL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application ELISA, IHC
Order details Cat. No. ABIN3180937
$359.79
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman
Application IF, IHC, ELISA
Order details Cat. No. ABIN2154106
$483.57
50 μL
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityMouse (Murine)
Application ICC, IHC, WB
Order details Cat. No. ABIN1860890
$252.00
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Rabbit, Polyclonal, IgG
ReactivityRat (Rattus)
Application WB
Order details Cat. No. ABIN6293078
$305.01
50 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN6711048
$350.00
100 μL
Plus shipping costs $45.00
Delivery in 6 to 11 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN6265813
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
Mouse, Monoclonal (2G3), IgG2a kappa
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN521178
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
Mouse, Monoclonal (2G10), IgG2a kappa
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN521177
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN5673152
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN5516838
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IHC, WB
Order details Cat. No. ABIN4964985
$295.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ELISA, IHC
Order details Cat. No. ABIN6099167
$337.67
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Order details Cat. No. ABIN6879156
$394.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityMouse (Murine)
Application WB
Order details Cat. No. ABIN2576210
$405.17
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Order details Cat. No. ABIN6921833
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Order details Cat. No. ABIN6838903
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Order details Cat. No. ABIN6822840
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Order details Cat. No. ABIN6911282
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Order details Cat. No. ABIN6895219
$416.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Rabbit, Polyclonal, IgG
ReactivityHuman
Application ELISA, IF, IHC
Order details Cat. No. ABIN5703141
$430.77
100 μg
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityHuman
Order details Cat. No. ABIN6863093
$438.90
100 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
Mouse, Monoclonal (1H5), IgG3 kappa
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN521180
ISO
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
Mouse, Monoclonal (2E4), IgG2a kappa
ReactivityHuman
Application ELISA
Order details Cat. No. ABIN521179
ISO
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
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TXK tyrosine Kinase (TXK) Antigen Profile

Protein Summary

Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T- cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420. Phosphorylation leads to TXK full activation. Contributes also to signaling from many receptors and participates in multiple downstream pathways, including regulation of the actin cytoskekleton. Like ITK, can phosphorylate PLCG1, leading to its localization in lipid rafts and activation, followed by subsequent cleavage of its substrates. In turn, the endoplasmic reticulum releases calcium in the cytoplasm and the nuclear activator of activated T-cells (NFAT) translocates into the nucleus to perform its transcriptional duty. With PARP1 and EEF1A1, TXK forms a complex that acts as a T-helper 1 (Th1) cell- specific transcription factor and binds the promoter of IFNG to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. Phosphorylates both PARP1 and EEF1A1. Phosphorylates also key sites in LCP2 leading to the up-regulation of Th1 preferred cytokine IL-2. Phosphorylates 'Tyr- 201' of CTLA4 which leads to the association of PI-3 kinase with the CTLA4 receptor.

Alternative names and synonyms associated with TXK tyrosine Kinase (TXK)

  • TXK tyrosine kinase (TXK) antibody
  • TXK tyrosine kinase (Txk) antibody
  • tyrosine-protein kinase TXK (LOC100544958) antibody
  • A130089B16Rik antibody
  • Btkl antibody
  • PSCTK5 antibody
  • PTK4 antibody
  • Rlk antibody
  • TKL antibody

Protein level used designations for TXK

PTK4 protein tyrosine kinase 4 , protein-tyrosine kinase 4 , resting lymphocyte kinase , tyrosine kinase , tyrosine-protein kinase TXK , PTK-RL-18 , TXK tyrosine kinase , tyrosine-protein kinase TXK-like , LOW QUALITY PROTEIN: tyrosine-protein kinase TXK

GENE ID SPECIES
7294 Homo sapiens
22165 Mus musculus
305311 Rattus norvegicus
444993 Sus scrofa
461344 Pan troglodytes
482139 Canis lupus familiaris
504782 Bos taurus
705104 Macaca mulatta
770387 Gallus gallus
100019276 Monodelphis domestica
100054343 Equus caballus
100341671 Oryctolagus cuniculus
100397226 Callithrix jacchus
100455862 Pongo abelii
100464564 Ailuropoda melanoleuca
100544958 Meleagris gallopavo
100598060 Nomascus leucogenys
100722451 Cavia porcellus
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