Browse our Catenin (Cadherin-Associated Protein), alpha 1, 102kDa Proteins (CTNNA1)

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

• catenin alpha 1 (CTNNA1)
• catenin (cadherin associated protein), alpha 1 (Ctnna1)
• catenin alpha 1 (Ctnna1)
• alpha Catenin (alpha-Cat)
• alpha Catenin (Dgri\alpha-Cat)
• Show all gene names
• catenin alpha-1 (Tsp_10127)
• catenin (cadherin-associated protein), alpha 1 (ctnna1)
• catenin alpha 1 S homeolog (ctnna1.S)

• 2010010M04Rik protein
• a-cat protein
• AA517462 protein
• AI988031 protein
• Alpha-Cat protein
• Show all synonym aliases
• alpha-catenin protein
• alpha-ctn protein
• alphacat protein
• cap102 protein
• catna1 protein
• CG17947 protein
• CT39986 protein
• ctnna protein
• ctnna1 protein
• Dalpha-cat protein
• DalphaC protein
• Dalphacat protein
• DgriGH19548 protein
• dgri_GLEANR_3829 protein
• Dmcatp protein
• Dmel\\CG17947 protein
• GH19548 protein

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