Browse our anti-Cytochrome B-245, alpha Polypeptide (CYBA) Antibodies

Full name:: anti-Cytochrome B-245, alpha Polypeptide Antibodies (CYBA)

On www.antibodies-online.com are 57 Cytochrome B-245, alpha Polypeptide (CYBA) Antibodies from 15 different suppliers available. Additionally we are shipping Cytochrome B-245, alpha Polypeptide Proteins (8) and many more products for this protein. A total of 70 Cytochrome B-245, alpha Polypeptide products are currently listed.

Synonyms:: b558, CYBA, MGC80750, nmf333, P22-PHOX, p22phox, zgc:66077

list all antibodies	Gene Name	GeneID	UniProt
	CYBA	1535	P13498
	CYBA	13057	Q61462
	CYBA	79129	Q62737
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Most Popular Reactivities for anti-Cytochrome B-245, alpha Polypeptide (CYBA) Antibodies

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Top referenced anti-Cytochrome B-245, alpha Polypeptide Antibodies

Human Polyclonal CYBA Primary Antibody for IHC (fro), IF (p) - ABIN750538 : Walton, Shin, Tajinda, Heusner, Kogan, Miyake, Chen, Tamura, Matsumoto: Adult neurogenesis transiently generates oxidative stress. in PLoS ONE 2012 (PubMed)
Show all 4 Pubmed References
Human Monoclonal CYBA Primary Antibody for WB - ABIN1042639 : Taylor, Jesaitis: Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics. in Methods in molecular biology (Clifton, N.J.) 2008 (PubMed)
Show all 3 Pubmed References
Human Monoclonal CYBA Primary Antibody for IHC (fro), FACS - ABIN1042638 : Taylor, Burritt, Baniulis, Foubert, Lord, Dinauer, Parkos, Jesaitis: Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
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More Antibodies against Cytochrome B-245, alpha Polypeptide Interaction Partners

Human Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

Three new mutations of CYBA gene in four of 22 Iranian patients with autosomal recessive-Chronic granulomatous disease were found.
Data indicate an association between the GA genotype of single nucleotide polymorphism rs3794624 in cytochrome b (show MT-CYB Antibodies)-245, alpha polypeptide (show ITGAE Antibodies) (CYBA) with decreased tuberculosis susceptibility in two Chinese populations.
in patients with very severe chronic obstructive pulmonary disease the NADPH oxidase subunit p22phox is significantly reduced as compared to controls; p22phox is a key player in COPD and in hypoxic pulmonary vascular remodelling
data demonstrated that rs4673 transition in p22phox gene may be involved in susceptibility to coronary artery disease and could be applied as a potential biomarker for this disease.
Data suggest that an SNP in NADPH oxidase (show NOX1 Antibodies) p22phox (C242T) is associated with nephropathy leading to macroalbuminuria in diabetic patients; this report is a meta-analysis of case-control genetic association studies. [META-ANALYSIS]
Together with the increased p22phox expression in lungs of asthmatic patients, findings demonstrate a crucial role of p22phox-dependent NADPH oxidase (show NOX1 Antibodies) for the development of mucus hypersecretion and airway hyperresponsiveness in house dust mite-induced model of asthma.
Results showed that variations of the C242T polymorphism of the CYBA gene altered the risk of developing neonatal respiratory distress syndrome, retinopathy of prematurity, and bronchopulmonary dysplasia.
In a family study of a patient with chronic granulomatous disease, the mutation in the CYBB (show CYBB Antibodies) gene was confirmed to be pathogenic, and the three variants in the CYBA gene were benign.
We demonstrated that rapid deletion of p22phox is possible and that the activity of Nox1 (show NOX1 Antibodies) and Nox4 (show NOX4 Antibodies) but not Nox5 (show NOX5 Antibodies) exclusively depends on p22phox.
NOX5 (show NOX5 Antibodies)-p22phox complex drives monocytic differentiation into dendritic cells, and thus could be critical for immunity and inflammation.

Mouse (Murine) Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

In p22phox(-/-) mice, hypoxic pulmonary vasoconstriction (HPV) was significantly impaired. In the chronic hypoxic setting, lack of p22phox was associated with improved right ventricular function and decreased pulmonary vascular remodelling.
Together with the increased p22phox expression in lungs of asthmatic patients, findings demonstrate a crucial role of p22phox-dependent NADPH oxidase (show NOX1 Antibodies) for the development of mucus hypersecretion and airway hyperresponsiveness in house dust mite-induced model of asthma.
Identification of a PPAR-gamma (show PPARG Antibodies) --> NF-kappaB (show NFKB1 Antibodies) --> p22phox neuroprotective signaling cascade opens a new avenue for protecting the brain against ischemic insult.
Knockout of the cytochrome P450 reductase by CRISPR/Cas9 technology (POR(-/-)) in HEK293 cells overexpressing Nox4 or Nox5 did not interfere with ROS production in intact cells. However, POR(-/-) abolished the signal in NADPH-stimulated assays using membrane fractions from the very same cells. Moreover, membranes of rat smooth muscle cells treated with angiotensin II showed an increased NADPH-dependent signal with lucigen
p22phox mRNA expression was increased in diet-induced obese (DIO) mice.
The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (show NOX1 Antibodies)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.
Vascular hnRNP-C expression is regulated by ROS (show ROS1 Antibodies) derived from NADPH (show FDXR Antibodies) oxidases and that the effects of NADPH oxidase (show NOX1 Antibodies) on vascular activation are mediated in part by protein kinase (show CDK7 Antibodies) CK1alpha (show CSNK1A1 Antibodies).
Enhanced p22(phox) expression causes vascular dysfunction through ERK1/2 and p38-mitogen-activated protein kinase (show MAPK14 Antibodies)-dependent mechanisms in male type 2 diabetic mice.
The first quantitative characterization of the interactions made between the cytosolic regulators NOXO1 (show NOXO1 Antibodies) and NOXA1 (show NOXA1 Antibodies) and membrane-bound p22(phox), is presented.
renal expression of Nox-2 (show CYBB Antibodies), p22(phox), and p47(phox), components of NADPH oxidase (show NOX1 Antibodies), are upregulated in GSD-Ia mice compared with controls

Pig (Porcine) Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis.
CRP (show CRP Antibodies) inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H (show NQO1 Antibodies) oxidase via p38 (show MAPK14 Antibodies) kinase activation
Reactive oxygen species generated by NADPH oxidase (show NOX1 Antibodies) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

Rabbit Cytochrome B-245, alpha Polypeptide (CYBA) interaction partners

Angiotensin II inhibits the Na+/K+ pump via protein kinase c epsilon (show PRKCE Antibodies)-dependent activation of NADPH oxidase (show NOX1 Antibodies) subunits.

Cytochrome B-245, alpha Polypeptide (CYBA) Antigen Profile

Antigen Summary

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.

Alternative names and synonyms associated with Cytochrome B-245, alpha Polypeptide (CYBA)

cytochrome b-245, alpha polypeptide (cyba) antibody
cytochrome b-245 alpha polypeptide L homeolog (cyba.L) antibody
cytochrome b-245, alpha polypeptide (CYBA) antibody
cytochrome b-245 alpha polypeptide (cyba) antibody
cytochrome b-245 light chain-like (LOC101328418) antibody
cytochrome b-245 alpha chain (CYBA) antibody
cytochrome b-245, alpha polypeptide (Cyba) antibody
cytochrome b-245 alpha chain (Cyba) antibody
p22-phox (CYBA) antibody

b558 antibody
CYBA antibody
MGC80750 antibody
nmf333 antibody
P22-PHOX antibody
p22phox antibody
zgc:66077 antibody

Protein level used designations for CYBA

, , , , , , , , , , , , , , , , , , , , , , , P22phox cytochrome b-245, alpha polypeptide predicted cytochrome b-245, alpha polypeptide Cytochrome b(558) alpha chain Cytochrome b558 subunit alpha Neutrophil cytochrome b 22 kDa polypeptide Superoxide-generating NADPH oxidase light chain subunit cytochrome b-245 light chain flavocytochrome b558 (p22phox) p22 phagocyte B-cytochrome cytochrome b light chain cytochrome b(558) alpha chain cytochrome b(558) alpha-subunit cytochrome b, alpha polypeptide cytochrome b558 subunit alpha flavocytochrome b-558 alpha polypeptide neutrophil cytochrome b 22 kDa polypeptide p22phox superoxide-generating NADPH oxidase light chain subunit cytochrome beta-558 p22 phox p22-phox cytochrome b558 alpha-subunit NADPH oxidase light chain subunit

GENE ID	SPECIES
393551	Danio rerio
446853	Xenopus laevis
489664	Canis lupus familiaris
549234	Xenopus (Silurana) tropicalis
100135693	Ovis aries
101328418	Tursiops truncatus
1535	Homo sapiens
13057	Mus musculus
79129	Rattus norvegicus
281111	Bos taurus
397507	Sus scrofa
100008800	Oryctolagus cuniculus

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