CYBA antibody

Catalog No. ABIN1042638

Cited in 2+ publications. The Mouse Monoclonal anti-CYBA antibody (Clone CS9) (ABIN1042638) specifically detects CYBA in WB, ELISA, IF, FACS, IHC (fro), ICC and IP. The antibody is reactive with Human samples.

Quick Overview for CYBA antibody (ABIN1042638)

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYBA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: CS9

Product Details anti-CYBA Antibody

Specificity: P22phox 165-KKPSE-169

Purification: Protein G purified

Immunogen: Partially purified human neutrophil flavocytochrome b (heparin Ultrogellectin affinity purification in octyl glucoside)

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try, WB: Use at 1:1000. Predicted molecular weight: 21 kDa ICC/IF: 1:100

Comment:

Myeloma, fusion partners: P3U1 myeloma

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Affinity purified antiserum containing PBS 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-CYBA antibody (ABIN1042638)

Taniguchi, Ohno: "ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 601-8, (2008) (PubMed).

Taylor, Burritt, Baniulis, Foubert, Lord, Dinauer, Parkos, Jesaitis: "Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 12, pp. 7349-57, (2004) (PubMed).

Target Details for CYBA

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Alternative Name: Cytochrome b245 Light Chain 

Background: Synonyms:
Superoxide-generating NADPH oxidase light chain subunit antibody,CYBA antibody,Cytochrome b(558) alphachain antibody,Cytochrome b558 subunit alpha antibody,Neutrophil cytochrome b 22 kDa polypeptide antibody,p22phagocyte B-cytochrome antibody,p22-phox antibody,p22phox antibody

Gene ID: 1535, 21577

OMIM: 608508

UniProt: Q01062

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis