Browse our Cystatin A (Stefin A) Proteins (CSTA)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

• cystatin A (CSTA)
• cystatin A1 (Csta1)
• cystatin A (Csta)
• cystatin A (CYSA)
• cystatin-A (LOC100725920)

• AREI protein
• ATCYSA protein
• CST protein
• CSTA protein
• cystatin A protein
• Show all synonym aliases
• FL3-27 protein
• STF1 protein
• STFA protein
• T20B5.8 protein
• T20B5_8 protein

cystatin AS , cystatin-A , stefin-A , cystatin A (stefin A) , cystatin-AS , stefin A