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CSTA Products

(Cystatin A (Stefin A) (CSTA))
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008].

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Featured CSTA Categories

CSTA Antibodies

High quality antibodies with extensive validation data.

CSTA ELISA Kits

Reliable ELISA kits for a wide range of species.

CSTA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CSTA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (5)
Cat. No. ABIN6939196
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
Cat. No. ABIN7148983
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6261071
Quantity 100 μL
Datasheet Datasheet

Recommended CSTA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN6574160
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955177
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955178
Quantity 96 tests
Datasheet Datasheet

Recommended CSTA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350599
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3120511
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3120510
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CSTA products

Mezzapesa, Bastelica, Crescence, Poggi, Grino, Peiretti, Panicot-Dubois, Dupont, Valero, Maraninchi, Bordet, Alessi, Dubois, Canault: "Increased levels of the megakaryocyte and platelet expressed cysteine proteases stefin A and cystatin A prevent thrombosis." in: Scientific reports, Vol. 9, Issue 1, pp. 9631, (2020) (PubMed).

Kan, Okabayashi, Yokota, Yamamoto, Fujii, Yamashita: "Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway." in: Journal of virology, Vol. 86, Issue 19, pp. 10338-46, (2012) (PubMed).

Eliyahu, Shtraizent, He, Chen, Shalgi, Schuchman: "Identification of cystatin SA as a novel inhibitor of acid ceramidase." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35624-33, (2011) (PubMed).

Vasilopoulos, Walters, Cork, Duff, Sagoo, Tazi-Ahnini: "Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5." in: European journal of human genetics : EJHG, Vol. 16, Issue 8, pp. 1002-9, (2008) (PubMed).

Asplund, Gry Björklund, Sundquist, Strömberg, Edlund, Ostman, Nilsson, Pontén, Lundeberg: "Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma." in: The British journal of dermatology, Vol. 158, Issue 3, pp. 527-38, (2008) (PubMed).

Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).

Synonyms and alternative names related to CSTA

cystatin A (CSTA), cystatin A1 (Csta1), cystatin A (Csta), cystatin A (CYSA), cystatin-A (LOC100725920), AREI, ATCYSA, CST, CSTA, cystatin A, FL3-27, STF1, STFA, T20B5.8, T20B5_8

Protein level used designations for CSTA

  • cystatin AS
  • cystatin-A
  • stefin-A
  • cystatin A (stefin A)
  • cystatin-AS
  • stefin A
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