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anti-Human CIRBP Antibodies:
anti-Mouse (Murine) CIRBP Antibodies:
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Cow (Bovine) Polyclonal CIRBP Primary Antibody for WB - ABIN2778761
Schroeder, Metzger, Miller, Rhen: A Novel Candidate Gene for Temperature-Dependent Sex Determination in the Common Snapping Turtle. in Genetics 2016
Show all 2 Pubmed References
Mouse (Murine) Polyclonal CIRBP Primary Antibody for ELISA, WB - ABIN4298802
Zeng, Kulkarni, Inoue, Getzenberg: Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity. in Journal of cellular biochemistry 2009
XCIRP is required to maintain the expression of adhesion molecules and cell movement during embryonic development.
Cold-inducible RNA binding protein XCIRP regulates anterior neural development in Xenopus.
Crystal structure of the hnRNP A18 RNA recognition motif has been reported.
cold temperature can induce an airway inflammatory response and excess mucus production via a CIRP-mediated increase in mRNA stability and protein translation
CIRP Expression Is Induced in Skin Cancer Cells and in Keratinocytes Exposed to Lower-Dose But Not Higher-Dose UVB Radiation.
In human abdominal aortic aneurysm (AAA (show APP Antibodies)) tissue, Cold-inducible RNA-binding protein (CIRP) exhibited a 5.6-fold and 93% increase in mRNA and protein expression, respectively. In a rat AAA (show APP Antibodies) model, CIRP was upregulated significantly in a time-dependent manner in the serum and AAA (show APP Antibodies) tissue.
We found out that the link between CIRP and Snail (show SNAI1 Antibodies) is mediated by ERK (show EPHB2 Antibodies) and p38 (show CRK Antibodies) pathways. EMT (show ITK Antibodies) is a critical component of carcinoma metastasis and invasion. As demonstrated in this study, the biological role of CIRP in EMT (show ITK Antibodies) may explain why CIRP overexpression has been associated with a bad prognosis in cancer patients.
CIRP was expressed in the bronchi of human COPD (show ARCN1 Antibodies) patients and was involved in inflammatory factors and MUC5AC expression after cold stimulation through the ERK (show EPHB2 Antibodies) and NF-kappaB (show NFKB1 Antibodies) pathways
Low CIRP expression is associated with colon Cancer.
this study shows that CIRP expression in bronchial airway epithelial cells of patients with chronic obstructive pulmonary disease is higher than that in healthy person
We generated a transgenic mouse model overexpressing human CIRP in the mammary epithelium to ask if it plays a role in mammary gland development. Effects of CIRP overexpression on mammary gland morphology, cell proliferation, and apoptosis were studied from puberty through pregnancy, lactation and weaning
Increased synovial fluid CIRP concentrations were closely associated with the severity of knee osteoarthritis
tissue damage induced NADPH oxidase (show NOX1 Antibodies) activation and increased the release of reactive oxygen species via cold-inducible RNA-binding protein (CIRP)-TLR4 (show TLR4 Antibodies)-MyD88 (show MYD88 Antibodies) signaling.
temperature-dependent accumulation of Cirbp mRNA is controlled primarily by the regulation of splicing efficiency, defined as the fraction of Cirbp pre-mRNA processed into mature mRNA
this paper shows that cold air stimulation induced MUC5AC expression in wild-type mice but not in CIRP-/-) mice.
state. These data collectively suggest that a deficiency in CIRP accelerates the wound healing process
These results can provide new insights into the molecular mechanisms of Cirp function.
Findings suggest that CIRP could exert protective effects against oxidative stress, and that it might be a novel neuroprotective agent
targeting CIRP offers potential therapeutic implications in the treatment of hepatic I/R injury.
Cirp appears to play a critical carcinogenic function and its expression might be a useful biomarker for hepatocellular carcinomas risk prediction.
Cirp promotes the development of intestinal inflammation and colorectal tumors through regulating apoptosis and production of TNFalpha (show TNF Antibodies) and IL23 (show IL23A Antibodies) in inflammatory cells.
alcohol exposure activates microglia to produce and secrete CIRP
Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to themm and inhibiting their deadenylation. Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis. Required for pronephros development (By similarity).
cold-inducible RNA-binding protein
, Glycine-rich RNA-binding protein CIRP
, glycine-rich RNA-binding protein CIRP
, hyperosmotic glycine rich protein-like
, Cold-inducible RNA-binding protein
, cold inducible RNA binding protein
, Cold-inducible RNA-binding protein-1
, Glycine-rich RNA-binding protein CIRP-A
, cold inducible RNA-binding protein
, cold-inducible RNA-binding protein 1
, cold-inducible RNA-binding protein A
, aggrecan promoter binding protein
, A18 hnRNP
, glycine-rich RNA binding protein
, cold-inducible RNA binding protein