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anti-Human EIF3D Antibodies:
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Human Polyclonal EIF3D Primary Antibody for IP, WB - ABIN408580
Chazal, Daguenet, Wendling, Ulryck, Tomasetto, Sargueil, Le Hir: EJC core component MLN51 interacts with eIF3 and activates translation. in Proceedings of the National Academy of Sciences of the United States of America 2013
results indicate that eIF3D plays a key role in the proliferation of AML cells, and suggest that eIF3D silencing might be a potential therapeutic strategy for leukemia.
eIF3d promotes gallbladder cancer (GBC) progression mainly via eIF3d-GRK2-AKT axis and it may be used as a prognostic factor. The therapeutic targeting of eIF3d-GRK2 axis may be a potential treatment approach for GBC.
A transcript-specific eIF3 complex mediates global translational control of energy metabolism.
Results provide evidences that EIF3D may function as a potential proto-oncogene that participates in the occurrence and progression of renal cell carcinoma.
Knockdown of eIF3D inhibited breast cancer cell proliferation and invasion.
eIF3d makes specific contacts with the RNA cap, as exemplified by cap analogue competition, and these interactions are essential for assembly of translation initiation complexes on eIF3-specialized mRNAs such as the cell proliferation regulator c-Jun
the critical involvement of EIF3D in the survival and progression of melanoma cells
EIF3D plays an important role in modulating glioma cell growth and migration.
Findings suggest that eukaryotic translation initiation factor 3 subunit D (eIF3D) might play an important role in colon cancer progression.
eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome.
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex.
eukaryotic translation initiation factor 3 subunit D
, eukaryotic translation initiation factor 3 subunit 7
, eukaryotic initiation factor
, eukaryotic translation initiation factor 3, subunit D
, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa
, eukaryotic translation initiation factor 3 subunit D-like
, eIF3 p66
, translation initiation factor eIF3 p66 subunit
, eukaryotic translation initiation factor 3, subunit 7 (zeta)
, translation initiation factor eIF3 p66
, eukaryotic translation initiation factor 3, subunit 7 zeta
, Eukaryotic translation initiation factor 3 subunit 7
, eukaryotic translation initiation factor 3, subunit 7 (zeta, 66/67 kDa)