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anti-Human BDNF Antibodies:
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Dog (Canine) Polyclonal BDNF Primary Antibody for IHC, WB - ABIN2777093
Hashimoto, Moriguchi, Yamashita, Mori, Nemoto, Okada, Hori, Noguchi, Kunugi, Ohnishi: Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. in Neuroscience research 2008
Show all 7 Pubmed References
Human Polyclonal BDNF Primary Antibody for CyTOF, FACS - ABIN4899237
Xapelli, Bernardino, Ferreira, Grade, Silva, Salgado, Cavadas, Grouzmann, Poulsen, Jakobsen, Oliveira, Zimmer, Malva: Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. in The European journal of neuroscience 2008
Show all 5 Pubmed References
Human Polyclonal BDNF Primary Antibody for IF (p), IHC (p) - ABIN1387788
Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014
Show all 2 Pubmed References
Human Monoclonal BDNF Primary Antibody for ICC, ELISA - ABIN1724944
Yoshida, Ishikawa, Niitsu, Nakazato, Watanabe, Shiraishi, Shiina, Hashimoto, Kanahara, Hasegawa, Enohara, Kimura, Iyo, Hashimoto: Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder. in PLoS ONE 2012
Human Monoclonal BDNF Primary Antibody for FACS, ICC - ABIN4283827
Lambert, Carlson, Formichella, Sappington, Ahlem, Calkins: Oral Delivery of a Synthetic Sterol Reduces Axonopathy and Inflammation in a Rodent Model of Glaucoma. in Frontiers in neuroscience 2017
Dog (Canine) Polyclonal BDNF Primary Antibody for WB - ABIN2777092
Galindo, Soslow, Brinkmeyer-Langford, Gupte, Smith, Sengsayadeth, Sawyer, Benson, Kornegay, Markham: Translating golden retriever muscular dystrophy microarray findings to novel biomarkers for cardiac/skeletal muscle function in Duchenne muscular dystrophy. in Pediatric research 2016
Human Polyclonal BDNF Primary Antibody for EIA, Func - ABIN115986
Hartog, Dittrich, Pieneman, Jansen, Frankl-Vilches, Lessmann, Lilliehook, Goldman, Gahr: Brain-derived neurotrophic factor signaling in the HVC is required for testosterone-induced song of female canaries. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Show all 3 Pubmed References
Human Polyclonal BDNF Primary Antibody for EIA, Func - ABIN115985
Miknyoczki, Wan, Chang, Dobrzanski, Ruggeri, Dionne, Buchkovich: The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice. in Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Show all 3 Pubmed References
Study results demonstrated that high intensity exercise provides limited additional benefit to learning of a novel locomotor pattern in neurologically intact adults, despite increases in circulating brain derived neurotrophic factor (BDNF). In addition, presence of a single nucleotide polymorphism on the BDNF gene did not moderate the magnitude of serum BDNF increases with high intensity exercise.
serum BDNF levels decreased with the increase in emotional abuse in self-harming adolescents
Ginkgo biloba extract increased exercise-induced production of BDNF.
Study indicates that antisense RNA of brain-derived neurotrophic factor (BDNF-AS) siRNA induces activation of the BDNF-TrkB (show NTRK2 Antibodies)-PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway following hypoxia/reoxygenation (H/R)-induced neurotoxicity. These findings will be useful toward the application of BDNF-AS siRNA for the treatment of neurodegenerative diseases.
Mixed models repeated measurement was used to examine the therapeutic effect and changes in BDNF and cytokine levels between the groups
urinary BDNF level test could evaluate the severity of lower urinary tract symptoms in benign prostatic hyperplasia patients.
High school Chinese Han students with different genotypes of BDNF Val66Met polymorphism and gender had different prevalence of depression, different severity of depression, different potential factors of depression and independent predictors of depression at different times after the 2008 Wenchuan earthquake, suggesting interactions after stresses among BDNF Val66Met polymorphism, gender and time course on depression.
Suggest that irisin (show FNDC5 Antibodies) exerts beneficial effect on mood in COPD (show ARCN1 Antibodies) patients, possibly by inducing the expression of BDNF in brain areas associated with reward-related processes involved in by depression.
BDNF expression is up-regulated in NSCLC samples. BDNF stimulation increases the synthesis of BDNF itself through activation of STAT3 (show STAT3 Antibodies) in lung cancer cells.
These findings provides evidence that gene-gene interactions between p11 (show S100A10 Antibodies), tPA (show PLAT Antibodies) and BDNF are all associated with post stroke depression.
Findings suggest that carriers of the BDNF-Met allele may exhibit greater vulnerability to anxiety disorders and anorexia nervosa, contributed by increased excitability of pyramidal neurons, due to the combination of decreased GABAergic innervation of distal dendrites and BDNF-mediated suppression of perisomatic inhibitory inputs.
the ZnT3 (show Slc30a3 Antibodies) null state removed synaptic zinc, it rather increased free zinc in the cytosol of brain cells, which appeared to increase MMP-9 (show MMP9 Antibodies) activity and BDNF levels. The present results suggest that zinc dyshomeostasis during the critical period of brain development may be a possible contributing mechanism for ASD (show GUSB Antibodies).
There was a significant decrease in the BDNF protein expression along with an increase in the mRNA expression of CRH (show CRH Antibodies), NR3C1 (show NR3C1 Antibodies), CART, and NPY (show NPY Antibodies) in intact females
Daily OMR (show ATP5A1 Antibodies) testing during the critical period leads to general visual function improvements accompanied by increased DA and BDNF in the retina, with this process being requisitely mediated by TrkB (show NTRK2 Antibodies) activation
The changes in the expression patterns of proBDNF, BDNF, and their receptors under the influence of chronic alcohol consumption in the depressive ASC (show STS Antibodies) strain and nondepressive CBA strain mice are different.
These results suggest that BDNF is implicated in MDMA-induced dependence and psychosis by activating the midbrain serotonergic and dopaminergic neurons.
newborn neurons improve social recognition persistence through a BDNF-independent mechanism.
Study shows long-term physical exercise in mice led to a significant increase in the synthesis and release of brain derived neurotrophic factor along with an alteration in the morphology of astrocytes in the dentate gyrus.
Mice exposed to aggressive confrontations exhibited a similar pattern of species-typical aggressive and non-aggressive behaviors on the first and the last session. Repeated aggressive confrontations promoted an increase in plasma corticosterone. Repeated sessions of social instigation or aggressive confrontation did not alter BDNF concentrations at the prefrontal cortex and hippocampus.
High-intensity acute exercise increased total Bdnf mRNA in hippocampus of sedentary mice.
One of the modulators of TOR (show FRAP1 Antibodies) is brain-derived neurotrophic factor (BDNF), which activates the TOR (show FRAP1 Antibodies) signaling pathway to promote protein synthesis, synapse strengthening, and the creation of new neural networks.findings demonstrate that TOR (show FRAP1 Antibodies) activation in old animals occurs in the early phase of consolidation, and follows a pattern identical to that of BDNF expression.
These results suggest an involvement of the BDNF/TrkB (show NTRK2 Antibodies) system in the regulation of food intake and energy balance in zebrafish, as in mammals
BDNF-TrkB (show NTRK2 Antibodies) influences the expression level of components of chemokine (show CCL1 Antibodies) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.
Light regulates the expression of the BDNF/TrkB2 (show NTRK2 Antibodies) system in the adult zebrafish retina.
Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (show RACGAP1 Antibodies) (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (show PARD3 Antibodies)) protein.
the results demonstrate that bdnf mediates non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons
The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB (show NTRK2 Antibodies) in zebrafish.
The cloning and analysis of three additional zebrafish (Danio rerio) BDNF gene exons and two associated promoters, is reported. Among them are two exons that generate a novel tripartite mature transcript
Loss of BDNF is a major cause of the developmental abnormalities seen with huntingtin (show HTT Antibodies) knockdown in zebrafish.
Together these results suggest an important role of BDNF in the maintenance and regeneration of the olfactory system.
BDNF suppresses neuromuscular junction maturation through cAMP-PKA signaling pathway
Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG Antibodies) .
These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.
In the Xenopus melanotrope, BDNF biosynthesis and processing occur along the secretory granule maturation axis, together with that of POMC (show POMC Antibodies)-derived alphaMSH (show POMC Antibodies), and that the light controls the biosynthesis and secretion of BDNF and of POMC (show POMC Antibodies) end-products.
BDNF released from the neural lobe of the pituitary gland acts as a neurohormone stimulating the secretory activity of the melanotrope cells in the intermediate pituitary lobe.
BDNF influences synaptic connectivity in multiple ways, promoting not only the morphological maturation of axonal arbors but also their stabilization, but also their stabilization.
BDNF, in addition to its neural and hormonal roles, can be released as a neurohormone from the neural pituitary lobe of X. laevis
BDNF induces glial cell proliferation as well as axonal outgrowth and myelination in vivo.
PACAP stimulates the expression of BDNF transcript IV.
Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin factor (BDNF) signaling pathway.
Taken together, these data indicate that recurrent tethering stress in sows over 4.5 years results in a loss of neurotrophic support by BDNF, mediated by an overactive neuroendocrine system.
FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (show MMP9 Antibodies) and MMP-2 (show MMP2 Antibodies), caspase-3 (show CASP3 Antibodies) and BDNF
These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin (show INS Antibodies) and leptin (show LEP Antibodies).
Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF.
Study showed that complex relationships exist between BDNF/TrkB (show NTRK2 Antibodies) gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence
In a monkey model, cortical BDNF and activity regulated cytoskeletal-associated protein ARC (show Arc Antibodies) expressions are strongly correlated with spontaneous physical activity.
A SNP is present in rhesus macaques and is able to affect BDNF peripheral levels, thus making this primate model a fundamental tool to study gene by environment interactions involving the BDNF gene.
In monkey the decline of the BDNF protein level started earlier in the sensory and motor neocortical areas than in the association neocortical areas.
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
, brain derived neurothrophic factor
, brain derived neurotrophic factor
, anorexia BDNF
, brain-derived neurotrophic factor
, neurotrophic factor