BDNF antibody (Brain-Derived Neurotrophic Factor) (AA 19-248)

Details for Product anti-BDNF Antibody No. ABIN1724944
Antigen
Epitope
AA 19-248
34
14
11
8
6
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3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
249
135
122
20
14
12
10
9
7
5
4
4
4
3
3
1
Host
Mouse
235
40
8
7
5
3
Clonality (Clone)
Monoclonal ()
Conjugate
This BDNF antibody is un-conjugated
28
14
11
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
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128
107
46
38
22
18
18
16
13
10
4
4
2
2
1
1
1
1
1
Options
Immunogen Purified recombinant fragment of human BDNF (AA 19-248) expressed in E. Coli.
Clone 3D9C5
Isotype IgG1
Purification Purified
Antigen
Alternative Name BDNF (BDNF Antibody Abstract)
Background The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. ,
Molecular Weight 27.8 kDa
Gene ID 627
HGNC 627
Pathways RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (ABIN1724944) anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (Image 1)
Image no. 2 for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (ABIN1724944) anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (Image 2)
Image no. 3 for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (ABIN1724944) anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (Image 3)
Image no. 4 for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (ABIN1724944) anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (Image 4)
Image no. 5 for anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (ABIN1724944) anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibody (Image 5)
Product cited in: Yoshida, Ishikawa, Niitsu, Nakazato, Watanabe, Shiraishi, Shiina, Hashimoto, Kanahara, Hasegawa, Enohara, Kimura, Iyo, Hashimoto: "Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder." in: PLoS ONE, Vol. 7, Issue 8, pp. e42676, 2012 (PubMed).