Browse our anti-FGF2 (FGF2) Antibodies

Mouse (Murine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. present study highlights the central role for FGF-2 in the progression and maintenance of newly acquired blood and lymphatic vessels in the cornea of HSV-1-infected mice in the absence of infectious virions

2. NF-kappaBmiR15abFGF/VEGFA (show VEGFA Antibodies) axis contributes to the impaired angiogenic capacity of bone marrowmesenchymal stem cells in high fat dietfed mice.

3. Fibroblast growth factor (FGF1 (show FGF1 Antibodies) and FGF2), but not vascular endothelial growth factor (VEGF (show VEGF Antibodies)) rescued Psen1 (show PSEN1 Antibodies)-/- cells from serum starvation induced apoptosis.In the absence of serum, FGF2 immunoreactivity was distributed diffusely in cytoplasmic and nuclear vesicles of wt and Psen1 (show PSEN1 Antibodies)-/- cells, as levels of FGF2 in nuclear and cytosolic fractions were not significantly different.

4. Knockout of the 18-kDa FGF-2 isoform significantly attenuated atherogenesis, reduced aortic plaques, reduced macrophage infiltration and suppressed oxidative stress in mice fed with a high fat diet at all-time points.

5. Data show that exostosin-like 2 (EXTL2 (show EXTL2 Antibodies)) controls fibroblast growth factor 2 (FGF2) signaling through regulation of heparan sulfate biosynthesis.

6. BMP4 (show BMP4 Antibodies) promotes survival of neural stem/progenitor cells by enhancing the anti-apoptotic function of Bcl-xL (show BCL2L1 Antibodies) via BMP4 (show BMP4 Antibodies)-Smad1 (show SMAD1 Antibodies)/5/8-Id1 (show ID1 Antibodies) signaling in the presence of FGF-2.

7. FGF2 signaling can regulate osteoblastic niche cells to support HSC (show FUT1 Antibodies) homeostasis in response to bone marrow damage

8. Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signaling.

9. altered glycosaminoglycans (GAG) distribution in mucopolysaccharidoses I (MPS I) chondrocytes, and altered GAG, FGF2 and Indian hedgehog (show IHH Antibodies) distribution in growth plates from MPS I mice, is reported.

10. Data show that LOX (show LOX Antibodies)-PP enhances adipogenesis at least partially through inhibition of FGF-2 receptor signaling.

Zebrafish Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. Results uncover a novel Sdc2 (show SDC2 Antibodies)-Tbx16-Fgf2 pathway that regulates epithelial cell morphogenesis.

Cow (Bovine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. activation of FGFR1 (show FGFR1 Antibodies) and FGFR2 (show FGFR2 Antibodies) by uterine- and endometrial-derived FGF2 stimulates PI3K/AKT (show AKT1 Antibodies) and mitogen-activated protein kinase (show MAPK1 Antibodies) pathways for development of the porcine uterus and improvement of litter size

2. Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Antibodies) and bFGF expression through the activation of AP-1 (show JUN Antibodies) and NF-kappaB (show NFKB1 Antibodies) in bovine mammary gland fibroblasts.

3. Data suggest THBS1 (thrombospondin-1 (show THBS1 Antibodies)) expression predominates in luteal endothelial cells; THBS2 (show THBS2 Antibodies) expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1 (show THBS1 Antibodies)/THBS2 (show THBS2 Antibodies) but up-regulate expression of FGF2.

4. Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA (show VEGFA Antibodies) during these specific windows.

5. FGF2 was crucial for luteal endothelial network formation.

6. Associations between reproduction and milk traits, and polymorphisms at the STAT5A (show STAT5A Antibodies) and FGF2 gene loci, were found with STAT5A (show STAT5A Antibodies) polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

7. FGF2 and FGF10 (show FGF10 Antibodies) regulate migratory activity of ovine trophoblast cells through MAPK (show MAPK1 Antibodies)-dependent pathways.

8. investigation of signaling mechanisms used by FGF2 to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 regulates IFNT production in trophoblasts by acting through protein kinase C-delta (show PKCd Antibodies)

9. Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

10. bFGF is oxidized by lysyl oxidase (show LOX Antibodies)

Human Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. levels of the angiogenesis mediators endoglin (show ENG Antibodies), HB-EGF (show HBEGF Antibodies), BMP-9 (show GDF2 Antibodies) and FGF-2 in patients with severe sepsis and septic shock

2. Our results suggest photodynamic therapy is effective in increasing the expression of bFGF gene, an important factor in periodontal tissue regeneration and could indicate periodontal tissue regeneration

3. High FGF2 expression is associated with gastric cancer.

4. Regulation of vascular smooth muscle cell calcification by syndecan-4 (show SDC4 Antibodies)/FGF-2/PKCalpha (show PKCa Antibodies) signalling and cross-talk with TGF-beta1 (show TGFB1 Antibodies).

5. evaluation of the presence and localization of FGF2 in human sperm cells, and determination of FGF2 levels in semen samples and its relationship with conventional semen parameters

6. We have presented evidence that FGF2 promotes myofibroblast apoptosis in vivo, antagonizes pro-fibrotic TGF-beta (show TGFB1 Antibodies) signaling, inhibits fibroblast activation and prevents transdifferentiation of non-fibroblasts into myofibroblasts, and promotes a less fibrotic gene expression paradigm [Review]

7. These results demonstrate that FGF-TGFbeta (show TGFB1 Antibodies) signaling antagonism is the primary regulator of the smooth muscle cell phenotype switch.

8. Results describe a novel role of FGF2 as a modulator of osteoblast and mesenchymal stromal cell function, and provide evidence for involvement of FGF2 in leukemia pathogenesis and chemo-resistance.

9. Under specific experimental conditions, secretion of IL-1beta (show IL1B Antibodies) and FGF2 is triggered by phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]-dependent formation of pores across the plasma membrane.

10. HDAC1 (show HDAC1 Antibodies) depletion activates cardiac mesenchymal stromal cells proangiogenic paracrine signaling in a basic fibroblast growth factor-dependent manner.

Rabbit Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. Continuous passive motion can promote b-FGF expression to enhance type III collagen (show COL3A1 Antibodies) synthesis at the tendon-bone interface in early stage of tendon-bone repair following acute rupture of supraspinatus tendon in rabbits.

Pig (Porcine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 (show AKT1 Antibodies) pathway.

2. The overlapping relationships of 3'UTR (show UTS2R Antibodies) ends between NUDT6 (show NUDT6 Antibodies) and FGF-2 genes, were analyzed.

3. FGF2 in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.

4. By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 from endothelial cells.

5. qPCR analysis demonstrated an increase in FGF-2 mRNA levels beginning on day 75 and on day 114 of pregnancy.

6. FGF2 activates FGFR (show FGFR2 Antibodies) which then represses the fibroblast activation of valvular interstitial cells.

7. FGF2 effectively blocks transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Antibodies))-mediated myofibroblast activation

8. upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar

Xenopus laevis Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. These results suggest that bFGF activation of neuronal FGFR1 (show FGFR1 Antibodies) generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.