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anti-Human FGF2 Antibodies:
anti-Mouse (Murine) FGF2 Antibodies:
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Guinea Pig Polyclonal FGF2 Primary Antibody for IF (cc), IF (p) - ABIN726425
Pan, Wang, Xiang, Shao: Delta-like 1 serves as a new target and contributor to liver fibrosis down-regulated by mesenchymal stem cell transplantation. in The Journal of biological chemistry 2011
Show all 12 Pubmed References
Human Polyclonal FGF2 Primary Antibody for ELISA, IHC (p) - ABIN3042812
Wang, Wang, Yao, Wu, Tang, Gu, Li: The fibroblast growth factor-2 arrests Mycobacterium avium sp. paratuberculosis growth and immunomodulates host response in macrophages. in Tuberculosis (Edinburgh, Scotland) 2015
Show all 6 Pubmed References
Human Polyclonal FGF2 Primary Antibody for WB - ABIN3042390
Zhou, Ma, Si, Li, Xu, Tu, Wang: MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis and growth. in Cancer letters 2013
Show all 6 Pubmed References
Human Monoclonal FGF2 Primary Antibody for IHC, ELISA - ABIN969137
Romanov, James, Sherrington, Pettitt: Basic fibroblast growth factor suppresses p53 activation in the neoplastic cells of a proportion of patients with chronic lymphocytic leukaemia. in Oncogene 2005
Show all 3 Pubmed References
Human Polyclonal FGF2 Primary Antibody for ELISA, IHC - ABIN6254910
Zhang, Chen, Wang, Yang, Li, Wang, Liu, Ye: Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase. in Oncotarget 2018
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Cow (Bovine) Polyclonal FGF2 Primary Antibody for IHC (p), IHC - ABIN269699
de Ruijter-Villani, van Boxtel, Stout: Fibroblast growth factor-2 expression in the preimplantation equine conceptus and endometrium of pregnant and cyclic mares. in Theriogenology 2013
Show all 2 Pubmed References
Human Monoclonal FGF2 Primary Antibody for IHC (fro), ELISA - ABIN2473612
Kalsheker, Watkins, Hill, Morgan, Stockley, Fick: Independent mutations in the flanking sequence of the alpha-1-antitrypsin gene are associated with chronic obstructive airways disease. in Disease markers 1991
Show all 4 Pubmed References
Human Monoclonal FGF2 Primary Antibody for IHC, ELISA - ABIN966137
Kim, Shin, Choi, Kim, Ahn, Lee, Park, Kim, Mok, Nam: A preliminary results of a randomized trial comparing monthly 5-flourouracil and cisplatin to weekly cisplatin alone combined with concurrent radiotherapy for locally advanced cervical cancer. in Cancer research and treatment : official journal of Korean Cancer Association 2009
Show all 2 Pubmed References
Human Monoclonal FGF2 Primary Antibody for ICC, IF - ABIN4311442
Akl, Nagpal, Ayoub, Tai, Prabhu, Capac, Gliksman, Goy, Suh: Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies. in Oncotarget 2016
the dual warhead-FGF2 conjugate may overcome the potential acquired resistance of FGFR1 (show FGFR1 Antibodies)-overproducing cancer cells towards single cytotoxic drugs.
FGF2 initiates CYGB (show CYGB Antibodies) transcription via the JNK (show MAPK8 Antibodies) pathway.
A strong stromal FGF-2 expression was associated with a significantly higher clinical stage and higher biochemical recurrence rate. Patients with strong stromal FGF-2 expression also had a significantly worse biochemical recurrence-free survival.
levels of the angiogenesis mediators endoglin (show ENG Antibodies), HB-EGF (show HBEGF Antibodies), BMP-9 (show GDF2 Antibodies) and FGF-2 in patients with severe sepsis and septic shock
Our results suggest photodynamic therapy is effective in increasing the expression of bFGF gene, an important factor in periodontal tissue regeneration and could indicate periodontal tissue regeneration
High FGF2 expression is associated with gastric cancer.
Regulation of vascular smooth muscle cell calcification by syndecan-4 (show SDC4 Antibodies)/FGF-2/PKCalpha (show PKCa Antibodies) signalling and cross-talk with TGF-beta1 (show TGFB1 Antibodies).
evaluation of the presence and localization of FGF2 in human sperm cells, and determination of FGF2 levels in semen samples and its relationship with conventional semen parameters
We have presented evidence that FGF2 promotes myofibroblast apoptosis in vivo, antagonizes pro-fibrotic TGF-beta (show TGFB1 Antibodies) signaling, inhibits fibroblast activation and prevents transdifferentiation of non-fibroblasts into myofibroblasts, and promotes a less fibrotic gene expression paradigm [Review]
These results demonstrate that FGF-TGFbeta (show TGFB1 Antibodies) signaling antagonism is the primary regulator of the smooth muscle cell phenotype switch.
present study highlights the central role for FGF-2 in the progression and maintenance of newly acquired blood and lymphatic vessels in the cornea of HSV-1-infected mice in the absence of infectious virions
NF-kappaBmiR15abFGF/VEGFA (show VEGFA Antibodies) axis contributes to the impaired angiogenic capacity of bone marrowmesenchymal stem cells in high fat dietfed mice.
Fibroblast growth factor (FGF1 (show FGF1 Antibodies) and FGF2), but not vascular endothelial growth factor (VEGF (show VEGF Antibodies)) rescued Psen1 (show PSEN1 Antibodies)-/- cells from serum starvation induced apoptosis.In the absence of serum, FGF2 immunoreactivity was distributed diffusely in cytoplasmic and nuclear vesicles of wt and Psen1 (show PSEN1 Antibodies)-/- cells, as levels of FGF2 in nuclear and cytosolic fractions were not significantly different.
Knockout of the 18-kDa FGF-2 isoform significantly attenuated atherogenesis, reduced aortic plaques, reduced macrophage infiltration and suppressed oxidative stress in mice fed with a high fat diet at all-time points.
Data show that exostosin-like 2 (EXTL2 (show EXTL2 Antibodies)) controls fibroblast growth factor 2 (FGF2) signaling through regulation of heparan sulfate biosynthesis.
BMP4 (show BMP4 Antibodies) promotes survival of neural stem/progenitor cells by enhancing the anti-apoptotic function of Bcl-xL (show BCL2L1 Antibodies) via BMP4 (show BMP4 Antibodies)-Smad1 (show SMAD1 Antibodies)/5/8-Id1 (show ID1 Antibodies) signaling in the presence of FGF-2.
FGF2 signaling can regulate osteoblastic niche cells to support HSC (show FUT1 Antibodies) homeostasis in response to bone marrow damage
Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signaling.
altered glycosaminoglycans (GAG) distribution in mucopolysaccharidoses I (MPS I) chondrocytes, and altered GAG, FGF2 and Indian hedgehog (show IHH Antibodies) distribution in growth plates from MPS I mice, is reported.
Data show that LOX (show LOX Antibodies)-PP enhances adipogenesis at least partially through inhibition of FGF-2 receptor signaling.
These results suggest that bFGF activation of neuronal FGFR1 (show FGFR1 Antibodies) generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.
activation of FGFR1 (show FGFR1 Antibodies) and FGFR2 (show FGFR2 Antibodies) by uterine- and endometrial-derived FGF2 stimulates PI3K/AKT (show AKT1 Antibodies) and mitogen-activated protein kinase (show MAPK1 Antibodies) pathways for development of the porcine uterus and improvement of litter size
Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Antibodies) and bFGF expression through the activation of AP-1 (show JUN Antibodies) and NF-kappaB (show NFKB1 Antibodies) in bovine mammary gland fibroblasts.
Data suggest THBS1 (thrombospondin-1 (show THBS1 Antibodies)) expression predominates in luteal endothelial cells; THBS2 (show THBS2 Antibodies) expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1 (show THBS1 Antibodies)/THBS2 (show THBS2 Antibodies) but up-regulate expression of FGF2.
Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA (show VEGFA Antibodies) during these specific windows.
FGF2 was crucial for luteal endothelial network formation.
Associations between reproduction and milk traits, and polymorphisms at the STAT5A (show STAT5A Antibodies) and FGF2 gene loci, were found with STAT5A (show STAT5A Antibodies) polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).
FGF2 and FGF10 (show FGF10 Antibodies) regulate migratory activity of ovine trophoblast cells through MAPK (show MAPK1 Antibodies)-dependent pathways.
investigation of signaling mechanisms used by FGF2 to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 regulates IFNT production in trophoblasts by acting through protein kinase C-delta (show PKCd Antibodies)
Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.
bFGF is oxidized by lysyl oxidase (show LOX Antibodies)
FOXO1 (show FOXO1 Antibodies)-suppressed miR (show MYLIP Antibodies)-424 regulates both the proliferation and osteogenic differentiation of mesenchymal stem cells via targeting FGF2.
Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 (show AKT1 Antibodies) pathway.
The overlapping relationships of 3'UTR (show UTS2R Antibodies) ends between NUDT6 (show NUDT6 Antibodies) and FGF-2 genes, were analyzed.
FGF2 in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.
By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 from endothelial cells.
qPCR analysis demonstrated an increase in FGF-2 mRNA levels beginning on day 75 and on day 114 of pregnancy.
FGF2 activates FGFR (show FGFR2 Antibodies) which then represses the fibroblast activation of valvular interstitial cells.
FGF2 effectively blocks transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Antibodies))-mediated myofibroblast activation
upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar
Continuous passive motion can promote b-FGF expression to enhance type III collagen (show COL3A1 Antibodies) synthesis at the tendon-bone interface in early stage of tendon-bone repair following acute rupture of supraspinatus tendon in rabbits.
Results uncover a novel Sdc2 (show SDC2 Antibodies)-Tbx16-Fgf2 pathway that regulates epithelial cell morphogenesis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
basic fibroblast growth factor bFGF
, fibroblast growth factor 2
, heparin-binding growth factor 2
, basic fibroblast growth factor
, Basic fibroblast growth factor
, Heparin-binding growth factor 2