Browse our anti-FGF2 (FGF2) Antibodies

Mouse (Murine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. BMP4 (show BMP4 Antibodies) promotes survival of neural stem/progenitor cells by enhancing the anti-apoptotic function of Bcl-xL (show BCL2L1 Antibodies) via BMP4 (show BMP4 Antibodies)-Smad1 (show SMAD1 Antibodies)/5/8-Id1 (show ID1 Antibodies) signaling in the presence of FGF-2.

2. FGF2 signaling can regulate osteoblastic niche cells to support HSC (show FUT1 Antibodies) homeostasis in response to bone marrow damage

3. Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signaling.

4. altered glycosaminoglycans (GAG) distribution in mucopolysaccharidoses I (MPS I) chondrocytes, and altered GAG, FGF2 and Indian hedgehog (show IHH Antibodies) distribution in growth plates from MPS I mice, is reported.

5. Data show that LOX (show LOX Antibodies)-PP enhances adipogenesis at least partially through inhibition of FGF-2 receptor signaling.

6. tissue engineered periosteum can deliver FGF-2, TGF-beta1 (show TGFB1 Antibodies), and ASCs to a mouse critical-sized femur defect and further optimization may yield improved bone allograft healing.

7. Thus, FGF-2 levels in hESCs culture systems can be manipulated to generate cells with longer telomere which would be advantageous in the applications of hESCs in regenerative medicine.

8. Low FGF2 expression is associated with cardiac ischemia and systolic dysfunction.

9. Mechanical strain stimulates vasculogenesis of embryonic stem cells by the intracellular messengers ROS (show ROS1 Antibodies), NO and calcium as well as by upregulation of angiogenesis guidance molecules and the angiogenic growth factors VEGF (show VEGFA Antibodies), FGF-2 and PDGF (show PDGFA Antibodies)-BB.

10. FGFR (show FGFR2 Antibodies) Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt (show WNT2 Antibodies) Signaling in FGF2 High Molecular Weight Isoform

Zebrafish Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. Results uncover a novel Sdc2 (show SDC2 Antibodies)-Tbx16-Fgf2 pathway that regulates epithelial cell morphogenesis.

Cow (Bovine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. activation of FGFR1 (show FGFR1 Antibodies) and FGFR2 (show FGFR2 Antibodies) by uterine- and endometrial-derived FGF2 stimulates PI3K/AKT (show AKT1 Antibodies) and mitogen-activated protein kinase (show MAPK1 Antibodies) pathways for development of the porcine uterus and improvement of litter size

2. Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Antibodies) and bFGF expression through the activation of AP-1 (show JUN Antibodies) and NF-kappaB (show NFKB1 Antibodies) in bovine mammary gland fibroblasts.

3. Data suggest THBS1 (thrombospondin-1 (show THBS1 Antibodies)) expression predominates in luteal endothelial cells; THBS2 (show THBS2 Antibodies) expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1 (show THBS1 Antibodies)/THBS2 (show THBS2 Antibodies) but up-regulate expression of FGF2.

4. Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA (show VEGFA Antibodies) during these specific windows.

5. FGF2 was crucial for luteal endothelial network formation.

6. Associations between reproduction and milk traits, and polymorphisms at the STAT5A (show STAT5A Antibodies) and FGF2 gene loci, were found with STAT5A (show STAT5A Antibodies) polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

7. FGF2 and FGF10 (show FGF10 Antibodies) regulate migratory activity of ovine trophoblast cells through MAPK (show MAPK1 Antibodies)-dependent pathways.

8. investigation of signaling mechanisms used by FGF2 to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 regulates IFNT production in trophoblasts by acting through protein kinase C-delta (show PKCd Antibodies)

9. Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

10. bFGF is oxidized by lysyl oxidase (show LOX Antibodies)

Human Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. Dysregulation of the FGF2 gene represents an opportunity to understand further, and possibly intervene upon, mechanisms of wound healing in diabetics with CKD.

2. Out of five FGF-2 Gene Polymorphism loci, the TA genotype of rs308442 in the osteoporosis group (40.2%) was higher than in the control group (29.5%) (p < 0.05). The rs308442 locus of FGF-2 gene is closely correlated to osteoporosis in this Zhuang ethnic Chinese cohort, and the TA may be the risk genotype of osteoporosis.

3. Up-regulation of FGF2 and down-regulation FAM201A were correlated with the development of osteonecrosis of the femoral head after femoral neck fracture.

4. over-expression, isolation, and biological activity of all recombinant human FGF2 isoforms, are reported.

5. We found that hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-196a-3p affected expression on both mRNA and protein levels of FGF2. our study provided evidence that a functional SNP rs1048201 was associated with bone mineral density (BMD (show BEST1 Antibodies)), and SNP rs1048201 variant may act by affecting binding of hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-196a-3p

6. Data show that mutant soluble ectodomain of FGFR2IIIc (msFGFR2c) but not wild-type soluble ectodomain of FGFR2IIIc (wsFGFR2c) could selectively bind to c subtype of FGFRs in the presence of FGF-2.

7. Furthermore, MERS coronavirus induced apoptosis through upregulation of Smad7 (show SMAD7 Antibodies) and fibroblast growth factor 2 (FGF2) expression in both kidney and lung cells.

8. The present work aims to investigate the relationship between the expression of AEG-1 (show MTDH Antibodies)(astrocyte elevated gene-1), b-FGF(basic-fibroblast growth factor), beta-catenin (show CTNNB1 Antibodies), Ki-67 (show MKI67 Antibodies), TNF-alpha (tumor necrosis factor (show TNF Antibodies)-alfa) other prognostic parameters in DC (Ductal Carcinomas) and ductal intraepithelial neoplasm. We found a relationship between these factors.

9. Studies indicate that therapeutically targeting FGF2 and FGFR (show FGFR2 Antibodies) has been extensively assessed in multiple preclinical studies and numerous drugs and treatment options have been tested in clinical trials.

10. FGF2 is involved in melanoma development and progression. HMW FGF2 isoforms enhance in vitro motility of melanoma cells. LMW FGF2 confers stem-like features and increases in vivo metastasization. LMW FGF2 promotes angiogenesis while HMW FGF2 induces vasculogenic mimicry.

Rabbit Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. Continuous passive motion can promote b-FGF expression to enhance type III collagen (show COL3A1 Antibodies) synthesis at the tendon-bone interface in early stage of tendon-bone repair following acute rupture of supraspinatus tendon in rabbits.

Pig (Porcine) Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 (show AKT1 Antibodies) pathway.

2. The overlapping relationships of 3'UTR (show UTS2R Antibodies) ends between NUDT6 (show NUDT6 Antibodies) and FGF-2 genes, were analyzed.

3. FGF2 in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.

4. By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 from endothelial cells.

5. qPCR analysis demonstrated an increase in FGF-2 mRNA levels beginning on day 75 and on day 114 of pregnancy.

6. FGF2 activates FGFR (show FGFR2 Antibodies) which then represses the fibroblast activation of valvular interstitial cells.

7. FGF2 effectively blocks transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Antibodies))-mediated myofibroblast activation

8. upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar

Xenopus laevis Fibroblast Growth Factor 2 (Basic) (FGF2) interaction partners

1. These results suggest that bFGF activation of neuronal FGFR1 (show FGFR1 Antibodies) generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.