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anti-SHC1 Antibodies

191 results:

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 385-495) Primary Antibody

SHC1 Reactivity: Human, Mouse ELISA, FACS, ICC, WB Host: Mouse Monoclonal 2F7C7 unconjugated
Catalog No. ABIN5542463
$448.80
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 424-440) Primary Antibody

SHC1 Reactivity: Human, Rat ICC, IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3044111
$240.00
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 536-564) Primary Antibody

SHC1 Reactivity: Human, Mouse, Rat IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043923
$280.00
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (C-Term) Primary Antibody

SHC1 Reactivity: Human, Mouse, Rat ICC, IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032555
$493.63
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 171-280) Primary Antibody

SHC1 Reactivity: Human IF, IHC (p), PLA, ELISA, WB Host: Mouse Monoclonal 3F4 unconjugated
Catalog No. ABIN562866
$600.00
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (pTyr349) Primary Antibody

SHC1 Reactivity: Human, Mouse, Rat ELISA, ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6255897
$390.77
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 8 to 9 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (pTyr427) Primary Antibody

SHC1 Reactivity: Human, Mouse, Rat ELISA, ICC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6255915
$390.77
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 8 to 9 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (AA 171-280) Primary Antibody

SHC1 Reactivity: Human ELISA, IF, IHC, IHC (p), PLA, WB Host: Mouse Monoclonal 3F4 unconjugated
Catalog No. ABIN574341
$924.00
Plus shipping costs $45.00
50 μg
local_shipping Shipping to: United States
Delivery in 11 to 14 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (Internal Region) Primary Antibody

SHC1 Reactivity: Human IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854910
$466.18
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1) (pSer36) Primary Antibody

SHC1 Reactivity: Human, Mouse, Rat ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed 1
Catalog No. ABIN745913
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Type Primary
    • Primary
  • Target SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
    • SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Tumor Protein P53 (TP53)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • CD4
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-kB p65 (NFkBP65)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Albumin (ALB)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD8a Molecule (CD8A)
    • CD19 Molecule (CD19)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Hemagglutinin (HA)
    • CD3 epsilon (CD3E)
    • Jun Proto-Oncogene (JUN)
    • Integrin alpha M (ITGAM)
    • Myc Proto-Oncogene protein (MYC)
    • CD44
    • Histone H4
    • Interleukin 6 (IL6)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD8
    • Vimentin (VIM)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Interleukin 2 (IL2)
    • VEGF Receptor 2 (VEGFR2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD5
    • Insulin Receptor Substrate 1 (IRS1)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Glial Fibrillary Acidic Protein (GFAP)
    • CD14
    • CD34
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Mucin 1 (MUC1)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Catenin, beta (CATNB)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Synuclein, alpha (SNCA)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Flow Cytometry (FACS)
    • Enzyme Immunoassay (EIA)
    • Proximity Ligation Assay (PLA)
    • Immunochromatography (IC)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Dog
    • Cow
    • Horse
    • Pig
    • Monkey
    • Guinea Pig
    • Rabbit
    • Xenopus laevis
    • Zebrafish (Danio rerio)
    • Bat
    • Chicken
    • Chimpanzee
    • Hamster
    • Sheep
  • Cited in publications
  • Images available
  • Preservative free only
  • Host
    • Rabbit
    • Mouse
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • 3F4
    • 2F7C7
    • 47F4
    • 1-00E-003
    • 1-50E-012
    • 11F6
    • 2-40E-005
    • 3A1
    • 3H1
    • 3J19
    • 6-00E-010
    • 6D758
    • 6E10
    • RB40722
  • Binding Specificity
    • pTyr349
    • pTyr427
    • pSer36
    • pTyr317
    • AA 378-405
    • AA 480-520
    • Center
    • pTyr350
    • Internal Region
    • C-Term
    • N-Term
    • AA 171-280
    • AA 207-370
    • AA 425-485
    • AA 481-583
    • Tyr349
    • Tyr427
    • pTyr239
    • AA 314-320
    • AA 315-364
    • AA 347-351
    • AA 424-440
    • AA 425-429
    • AA 536-564
    • pTyr240
    • AA 10-90
    • AA 272-559
    • AA 290-370
    • AA 300-350
    • AA 366-473
    • AA 370-450
    • AA 371-420
    • AA 385-495
    • AA 393-442
    • AA 413-443
    • Glu343
    • Leu421
    • Middle Region
    • Tyr1069
    • Tyr1092
    • Tyr240
  • Conjugate
    • Un-conjugated
    • Biotin
    • FITC
    • Alexa Fluor 750
    • HRP
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 350
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • APC
    • Alkaline Phosphatase (AP)
    • PE
  • Isotype
    • IgG
    • IgG1
    • IgG1 kappa
    • Ig Fraction
    • IgG kappa
  • Format
    • Liquid
    • Lyophilized

SHC1 Antigen Profile

Protein Summary

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SHC1

  • SHC adaptor protein 1 (SHC1) antibody
  • Shc1p (SHC1) antibody
  • squalene--hopene cyclase (shc1) antibody
  • SHC adaptor protein 1 (Shc1) antibody
  • SHC (Src homology 2 domain containing) transforming protein 1 (shc1) antibody
  • SHC (Src homology 2 domain containing) transforming protein 1 L homeolog (shc1.L) antibody
  • src homology 2 domain-containing transforming protein C1 (Shc1) antibody
  • p66 antibody
  • p66shc antibody
  • Shc antibody
  • SHC1 antibody
  • ShcA antibody
  • si:dkey-246i14.4 antibody
  • wu:fc10h03 antibody

Protein level used designations for SHC1

SHC (Src homology 2 domain containing) transforming protein 1 , Shc1p , Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH , squalene--hopene cyclase , SH2 domain protein C1 , SHC-transforming protein 1 , src homology 2 domain-containing-transforming protein C1 , SHC-transforming protein 1-like , SHC (Src homology 2 domain-containing) transforming protein 1 , SHC-transforming protein 3 , SHC-transforming protein A , src homology 2 domain-containing transforming protein C1 , p60Shc , src homology collagen , adaptor protein SHC

GENE ID SPECIES
457351 Pan troglodytes
856832 Saccharomyces cerevisiae S288c
4234272 Frankia alni ACN14a
4944146 Saccharopolyspora erythraea NRRL 2338
100016090 Monodelphis domestica
100063053 Equus caballus
100173225 Pongo abelii
100390337 Callithrix jacchus
100480856 Ailuropoda melanoleuca
100540048 Meleagris gallopavo
100606068 Nomascus leucogenys
100229782 Taeniopygia guttata
6464 Homo sapiens
85385 Rattus norvegicus
323818 Danio rerio
399198 Xenopus laevis
395934 Gallus gallus
490439 Canis lupus familiaris
507196 Bos taurus
20416 Mus musculus

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