Goat anti-Mouse IgM Antibody (FITC)

Catalog No. ABIN2176891

Quick Overview for Goat anti-Mouse IgM Antibody (FITC) (ABIN2176891)

Target: IgM

Clonality: Polyclonal

Conjugate: FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Isotype: IgM

Product Details

Reactivity: Mouse

Host: Goat

Purification: Purified by Protein A.

Application Details

Application Notes: IF(IHC-P): (1:500-2000), IF(IHC-F): (1:500-2000), IF(ICC): (1:500-1000)
Optimal working dilution should be determined by the investigator.

Comment:

Exitation/Emission: 494nm/518nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4 °C for 12 months.

References

Jiang, Bian, Ma, Liu, Yang, Zhu, Xu, Zheng, Qiao, Shuai, Zhou, Huang: "Eryptosis as an Underlying Mechanism in Systemic Lupus Erythematosus-Related Anemia." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 40, Issue 6, pp. 1391-1400, (2016) (PubMed).

Xin, Yang, Fan, Zhao, Ouyang, Liu, Zhao, Li, Song, Yang, Zou, Yan, Zeng, Lai: "Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs." in: PLoS ONE, Vol. 8, Issue 12, pp. e84250, (2013) (PubMed).

Target Details

Target: IgM

Target Type: Antibody

Background: Immunoglobulin IgM normally constitutes about 10 % of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells.