Mouse anti-Human IgA Antibody
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- Target See all IgA products
- IgA
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Anti-Hu IgA Purified
- Specificity
- The mouse monoclonal antibody AD2.947 reacts with human IgA1 and IgA2.
- Purification
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- Immunogen
- human IgA
- Clone
- AD2-947
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- IgA
- Abstract
- IgA Products
- Target Type
- Antibody
- Background
- Immunoglobulin A (IgA) is the major immunoglobulin class in body secretions that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. Its serum concentration is approximately 0.2 g/l and biological survival (T1/2 in plasma) 6 days. Plasma IgA is predominantly monomeric (160 kDa) and of the IgA1 subclass, and is mostly produced in the bone marrow. Over half of IgA produced by the intestinal lamina propria plasmocytes is in oligomeric form and 35 % of it is IgA2.,Immunoglobulin A
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