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anti-Mouse (Murine) Filaggrin Antibodies:
anti-Human Filaggrin Antibodies:
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Human Monoclonal Filaggrin Primary Antibody for FACS, IF - ABIN5578197
Gan, McBride, Idler, Markova, Steinert: Organization, structure, and polymorphisms of the human profilaggrin gene. in Biochemistry 1991
Loss of epidermal AP1 (show JUN Antibodies) reduces filaggrin level, alters chemokine (show CCL1 Antibodies) expression and produces an ichthyosis (show LBR Antibodies)-related phenotype.
FGFR1 (show FGFR1 Antibodies) is a driver oncogene (show RAB1A Antibodies) in de novo, FGFR1 (show FGFR1 Antibodies)-overexpressing acute myeloid leukemia (show BCL11A Antibodies)
Visceral adipose tissue-derived factors stimulate cell transformation through FGFR-1 (show FGFR1 Antibodies).
the localization of FGF9 and its receptors at different embryonic and postnatal stages in mice testes, was examined.
CDC42 (show CDC42 Antibodies) is involved in the trafficking of FGF receptors to the cell membrane to regulate epicardium formation.
MAPK (show MAPK1 Antibodies) cascades participate in osteogenesis, but only the ERK (show EPHB2 Antibodies) signaling pathway responds to FGFR1 (show FGFR1 Antibodies).
It is well accepted that myelin is a biologically active membrane in active communication with the axons. However, the axonal signals, the receptors on myelin, and the integration of intracellular signaling pathways emanating downstream from these receptors that drive the growth of the myelin sheath remain poorly understood in the CNS. This study brings up the intriguing possibility that FGF receptor (show FGFR2 Antibodies) 2, in the oligodendr
data suggest that FGF2 (show FGF2 Antibodies) levels are critically related to anxiety behavior and hypothalamic pituitary- adrenal axis activity, likely through modulation of hippocampal glucocorticoid receptor (show NR3C1 Antibodies) expression, an effect that is likely receptor mediated, albeit not by FGFR1 (show FGFR1 Antibodies), FGFR2 (show FGFR2 Antibodies), and FGFR3 (show FGFR3 Antibodies).
increased activity of the PI3K/AKT (show AKT1 Antibodies) signaling pathway in Pelo (show PELO Antibodies)-deficient skin might conflict with the dephosphorylation of profilaggrin and thereby affect its proper processing into filaggrin monomers and ultimately the epidermal differentiation
clearly demonstrate the different specificity of FGF12 (show FGF12 Antibodies)-FGFR1c2 and FGF22 (show FGF22 Antibodies)-FGFR1c2 for well defined HS structures and suggest that it is now possible to chemoenzymatically synthesize precise HS polysaccharides that can selectively mediate growth factor signaling
FLG (show FGFR1 Antibodies) and POSTN (show POSTN Antibodies) expression may be downregulated and upregulated, respectively, in the esophageal mucosa of patients with active eosinophilic esophagitis, and these changes may be restored with treatment in a significant percentage of cases.
immunoreactivity for filaggrin was significantly more intense in the oral mucosa in the patients with OLP/OLL compared with healthy controls
atopic dermatitis patients without palmoplantar hyperlinearity unlikely to carry FLG (show FGFR1 Antibodies) mutations
FLG (show FGFR1 Antibodies) mutations are strongly associated with atopic eczema and confer a significant risk of allergic sensitization and asthma in the context of eczema in Polish children.
There was no association of the atopy risk variants in the FLG (show FGFR1 Antibodies) gene with OFG.
suggest that FLG (show FGFR1 Antibodies) P478S is a kind of disease modifier which affects serologic parameters such as EDN (show RNASE2 Antibodies) and ECP (show ECP Antibodies)
In this study of 97 174 individuals from the Danish general population, FLG (show FGFR1 Antibodies) loss-of-function mutations were associated with increased ischemic stroke risk
study found that among patients with atopic dermatitis (AD), common FLG (show FGFR1 Antibodies) null mutations are associated with earlier AD onset in a dose-dependent manner, whereas TSLP (show TSLP Antibodies) rs1898671 appears unrelated to the timing of AD onset
The two SNPs K4671X and rs3126085 of FLG (show FGFR1 Antibodies) were related to Epstein-Barr virus (EBV)-associated gastric carcinoma.
FLG mutation is associated with IgE sensitization to peanut but not to other allergens in Swedish children up to 16 years of age
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
, basic fibroblast growth factor receptor 1
, proto-oncogene c-Fgr
, epidermal filaggrin
, Filaggrin (profilaggrin)
, keratin intermediate filament-associated protein