anti-MRPS12 Antibodies

Protein Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene\; all three variants encode the same protein.

Alternative names and synonyms associated with MRPS12

• mitochondrial ribosomal protein S12 (MRPS12) antibody
• mitochondrial ribosomal protein S12 (Mrps12) antibody
• technical knockout (tko) antibody
• mitochondrial ribosomal protein S12 L homeolog (mrps12.L) antibody
• 40S ribosomal protein S12, mitochondrial (LOC409723) antibody
• Show all gene names
• mitochondrial ribosomal protein S12 (mRpS12) antibody
• mitochondrial ribosomal protein S12 (mrps12) antibody
• putative mitochondrial 37S ribosomal protein MRPS12 (MRPS12) antibody
• putative mitochondrial 37S ribosomal protein MRPS12 (CAALFM_C106070WA) antibody
• mitochondrial ribosomal protein S12 (mrpS12) antibody
• fragile site, aphidicolin type, common, fra(6)(p22.2) (FRA6C) antibody

• AI327385 antibody
• CG7925 antibody
• Dmel\\CG7925 antibody
• EG:BACH59J11.1 antibody
• GB10531 antibody
• Show all synonym aliases
• l(1)3Ab antibody
• l(1)tko antibody
• MGC64304 antibody
• MPR-S12 antibody
• MRP-S12 antibody
• mRpS12 antibody
• mt-rps12 antibody
• Rpms12 antibody
• rps12 antibody
• RPSM12 antibody
• S12 antibody
• Tko antibody

Protein level used designations for MRPS12

28S ribosomal protein S12, mitochondrial , MRP-S12 , S12mt , MT-RPS12 , mitoribosomal protein s12 , ribosomal protein, mitochondrial, S12 , CG7925-PB , CG7925-PC , mitochondrial ribosomal protein S12 , mitoribosomal protein S12 , tko-PB , tko-PC , Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins , Mrps12p , likely mitochondrial ribosomal protein S12