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The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)
, amyloid beta (A4) precursor protein-binding, family A, member 2
, amyloid beta A4 precursor protein-binding, family A, member 2
, amyloid beta A4 precursor protein-binding family A member 2
, X11-like protein
, adapter protein X11beta
, neuron-specific X11L protein
, neuronal munc18-1-interacting protein 2
, phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
, Mint 2
, neuronal Munc18-1-interacting protein 2
, amyloid beta (A4) precursor protein-binding family A member 2 (X11-like)