Browse our anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Antibodies

Full name:: anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Antibodies (APBA2)

On www.antibodies-online.com are 86 Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Antibodies from 25 different suppliers available. Additionally we are shipping Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Proteins (4) and Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Kits (2) and many more products for this protein. A total of 98 Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 products are currently listed.

Synonyms:: D15S1518E, HsT16821, LIN-10, MGC83599, MGC:14091, Mint2, mXllL, X11-BETA, X11-like, X11L, XllL

list all antibodies	Gene Name	GeneID	UniProt
	APBA2	321	Q99767
	APBA2	11784	P98084
	APBA2	83610	O35431
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Most Popular Reactivities for anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Antibodies

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All available anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Antibodies

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Relevant Pathways for anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Antibodies

Synaptic Vesicle Exocytosis

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More Antibodies against Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 Interaction Partners

Human Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) interaction partners

These results support the hypothesis that APBA2 gene expression in different areas of Alzheimer's patient's brains.
Mints are necessary for activity-induced APP (show APP Antibodies) and PS1 (show PSEN1 Antibodies) trafficking and provide insight into the cellular fate of APP (show APP Antibodies) in endocytic pathways essential for Abeta (show APP Antibodies) production.
Aberrant MINT2 methylation in body fluids may predict peritoneal micrometastasis for gastric cancer (GC) patients, which is a potential poor prognostic factor in GC.
a significant difference was shown for APBA2 gene expression of peripheral lymphocytes between Chinese Han Tourette syndrome (TS) group and healthy controls idicating the APBA2 gene is a promising peripheral blood biomarker that discriminates between patients with TS and healthy subjects
Amyloid beta A4 precursor protein-binding family A member 2 contains a potent neuronal promoter whose activity may be regulated by DNA methylation (show HELLS Antibodies) and glucocorticoid receptor (show NR3C1 Antibodies) [alpha], paired box protein 5 (show CAPS Antibodies).
The co-occurrence of two nonsynonymous mutations in both affected siblings in a single family, each transmitted from a different unaffected parent, suggest a role for APBA2 mutations in rare individuals with ASD (show ARSD Antibodies).
APBA2 were genes activated in early endometrial endometrioid carcinoma (stages I-II).
X11beta-mediated reduction in cerebral Abeta (show APP Antibodies) is associated with cognition and long-term potentiation in Alzheimer's disease APPswe transgenic mice.
Interaction of transcriptional coactivators with Mint1 (show APBA1 Antibodies) or Mint2 prevents nuclear localization and transactivation of the transduction network mediated by amyloid precursor protein (show APP Antibodies).
The APBA2 gene has been found to map to a more telomeric location in chromosome 15q13 than previously found, and is partially duplicated within the broader region located approximately 5 Mb distal to the intact locus.

Mouse (Murine) Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) interaction partners

Results indicate that both X11 (show APBA1 Antibodies) and X11L exert largely in brain neurons, but X11 (show APBA1 Antibodies) may also function in peripheral tissues.
X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice
X11L suppresses the amyloidogenic but not amyloidolytic processing of APP (show APP Antibodies) in regions of the brain such as the hippocampus, which express significant levels of X11L.
shuttled between the cytoplasm and nucleus, the former more effectively than the latter; leptomycin B (LMB) induced substantial nuclear accumulation of EGFP-X11L
X11s associate primarily with APP (show APP Antibodies) molecules that are outside of DRM (show GREM1 Antibodies), that the dissociation of APP (show APP Antibodies)-X11 (show APBA1 Antibodies)/X11L complexes leads to entry of APP (show APP Antibodies) into DRM (show GREM1 Antibodies), and that cleavage of uncomplexed APP (show APP Antibodies) by BACE (show BACE Antibodies) within DRM (show GREM1 Antibodies)
This study suggested X11L is involved in the development of neuronal circuits that contribute to conflict resolution.

Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2)

amyloid beta precursor protein binding family A member 2 (APBA2) antibody
amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog (apba2.L) antibody
amyloid beta (A4) precursor protein-binding, family A, member 2 (Apba2) antibody
amyloid beta precursor protein binding family A member 2 (Apba2) antibody

D15S1518E antibody
HsT16821 antibody
LIN-10 antibody
MGC83599 antibody
MGC:14091 antibody
Mint2 antibody
mXllL antibody
X11-BETA antibody
X11-like antibody
X11L antibody
XllL antibody

Protein level used designations for APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like) , amyloid beta (A4) precursor protein-binding, family A, member 2 , amyloid beta A4 precursor protein-binding, family A, member 2 , amyloid beta A4 precursor protein-binding family A member 2 , X11-like protein , adapter protein X11beta , mint-2 , neuron-specific X11L protein , neuronal munc18-1-interacting protein 2 , phosphotyrosine-binding/-interacting domain (PTB)-bearing protein , Mint 2 , neuronal Munc18-1-interacting protein 2 , amyloid beta (A4) precursor protein-binding family A member 2 (X11-like)

GENE ID	SPECIES
100059336	Equus caballus
447055	Xenopus laevis
453697	Pan troglodytes
514762	Bos taurus
321	Homo sapiens
11784	Mus musculus
83610	Rattus norvegicus
415386	Gallus gallus
488700	Canis lupus familiaris
100172037	Pongo abelii

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