Browse our anti-CD4 (CD4) Antibodies

Full name:: anti-CD4 Molecule Antibodies (CD4)

On www.antibodies-online.com are 2199 CD4 Molecule (CD4) Antibodies from 46 different suppliers available. Additionally we are shipping CD4 Kits (75) and CD4 Proteins (73) and many more products for this protein. A total of 2372 CD4 products are currently listed.

Synonyms:: cd4, CD4mut, L3T4, Ly-4, p55, W3/25

list all antibodies	Gene Name	GeneID	UniProt
Anti-Mouse CD4	CD4	12504	P06332
Anti-Human CD4	CD4	920	P01730
Anti-Rat CD4	CD4	24932	P05540
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Most Popular Reactivities for anti-CD4 (CD4) Antibodies

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anti-Mouse (Murine) CD4 Antibodies:

anti-Human CD4 Antibodies:

anti-Rat (Rattus) CD4 Antibodies:

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Relevant Pathways for anti-CD4 Antibodies

CXCR4-mediated Signaling Events

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Top referenced anti-CD4 Antibodies

Mouse (Murine) Monoclonal CD4 Primary Antibody for BR, IHC (f) - ABIN2689225 : Regnier-Vigouroux, Blanc, Pont, Marchetto, Pierres: Accessory molecules and T cell activation. I. Antigen receptor avidity differentially influences T cell sensitivity to inhibition by monoclonal antibodies to LFA-1 and L3T4. in European journal of immunology 1987 (PubMed)
Show all 15 Pubmed References
Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689237 : Bendelac: Mouse NK1+ T cells. in Current opinion in immunology 1995 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for BR, CyTox - ABIN1176846 : Bierer, Sleckman, Ratnofsky, Burakoff: The biologic roles of CD2, CD4, and CD8 in T-cell activation. in Annual review of immunology 1989 (PubMed)
Show all 14 Pubmed References
Dog (Canine) Polyclonal CD4 Primary Antibody for ICC, IF - ABIN439030 : Hwang, Ahn, Park, Ha, Song, Jee: An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells. in Immunology letters 2011 (PubMed)
Show all 14 Pubmed References
Mouse (Murine) Monoclonal CD4 Primary Antibody for IHC (f), IHC (fro) - ABIN2689224 : Allman, Li, Hardy: Commitment to the B lymphoid lineage occurs before DH-JH recombination. in The Journal of experimental medicine 1999 (PubMed)
Show all 13 Pubmed References
Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689236 : Bosselut, Zhang, Ashe, Kopacz, Samelson, Singer: Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction. in The Journal of experimental medicine 1999 (PubMed)
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Human Monoclonal CD4 Primary Antibody for BP, FACS - ABIN4292796 : Wilson, Crowley, Odgers, Shaw: Immunofluorescent labeling using covalently linked anti-phycoerythrin antibodies and phycoerythrin polymers. in Cytometry 1991 (PubMed)
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Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689223 : Frederickson, Basch: L3T4 antigen expression by hemopoietic precursor cells. in The Journal of experimental medicine 1989 (PubMed)
Show all 11 Pubmed References
Mouse (Murine) Monoclonal CD4 Primary Antibody for FACS - ABIN2689238 : Godfrey, Kennedy, Mombaerts, Tonegawa, Zlotnik: Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. in Journal of immunology (Baltimore, Md. : 1950) 1994 (PubMed)
Show all 11 Pubmed References
Rat (Rattus) Monoclonal CD4 Primary Antibody for ICC, FACS - ABIN2749065 : Viel, Lemarié, Benkirane, Paradis, Schiffrin: Immune regulation and vascular inflammation in genetic hypertension. in American journal of physiology. Heart and circulatory physiology 2010 (PubMed)
Show all 10 Pubmed References

More Antibodies against CD4 Interaction Partners

Mouse (Murine) CD4 Molecule (CD4) interaction partners

data showed the critical role of the first extracellular domain of CD4, by obtaining mice with a loss of function mutation from Ile to Asn at the position 99 of CD4 (I99N).
results suggest that CD4 CD8 (show CD8A Antibodies) double knockout (DN)T cells can develop efficiently in vivo and chronic exposure to bacterial superantigens may precipitate a lupus-like autoimmune disease through activation of DNT (show NT5C Antibodies) cells
TCF-1-deficient CD4+ CD8+ double positive thymocytes fail to undergo TCR alpha Valpha14-Jalpha18 rearrangement and produce significantly fewer Natural killer T cells.
High-fat diet - induced type 2 diabetes decreases the number of ileum IL17 (show IL17A Antibodies)/RORgammaT CD4 T cells.
Results indicate that hypomethylation of Cd4 antigen correlates with stable CD4 expression.
CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase (show YES1 Antibodies) p56lck (show LCK Antibodies)
This study establishes an important role of IgE in abdominal aortic aneurysms pathogenesis by activating CD4+ T cells, mast cells, and macrophages.
5-kb cis (show CISH Antibodies)-element is required in postselection thymocytes for helper lineage commitment, presumably mediating the maintenance of CD4 expression, and suggest that inactivation of the cis (show CISH Antibodies)-element by DNA methylation (show HELLS Antibodies)
Both type I CD8 (show CD8A Antibodies)+ cytotoxic (Tc1 (show C8orf4 Antibodies)) cells and interleukin (IL)-17 (show IL17A Antibodies)-producing CD8 (show CD8A Antibodies)+ (Tc17) cells mediate effective antitumor immunity through distinct effector mechanisms, but Tc1 (show C8orf4 Antibodies) cells are superior to Tc17 cells in mediating tumor regression.
Accumulation of CD4 positive effector T cells is a critical step in the progression from mild glomerulonephritis to severe crescentic glomerulonephritis accompanied by tubulointerstitial inflammation and loss of kidney function.

Human CD4 Molecule (CD4) interaction partners

Human BD-2 (show DEFB4 Antibodies) and BD-3 (show DEFB103A Antibodies) play a positive and negative regulatory role in development and proliferation of human effector CD4+ T cells which is essential for optimal adaptive immune responses and the control of immunopathology.
These findings highlight regions of cross talk between gp120 (show ITIH4 Antibodies) and gp41 and identify heptad repeat region 1(HR1) residues that play important roles in regulating CD4-induced conformational changes in Env (show ERVW-1 Antibodies).
CD4(+) and CD19 (show CD19 Antibodies)(+) peripheral lymphocytes of early stage AD patients exhibit mitochondrial depletion, as seen both at the level of DNA and protein
Human microRNAs-221 and -222 inhibit HIV-1 entry in macrophages by targeting the CD4 viral receptor.
CD4 has four ecto (show TRIM33 Antibodies)-domains (D1-D4), D1, D2, and D4 each contain a distinctive disulfide bond. Reduction of D2 disulfide decreases the dynamics of its surrounding beta-strands. Favorable inward collapse of structure occurs around the D2 disulfide after reduction.
Long-term lung function decline in asthma is associated with elevation of bronchial CD8 and CD4 at baseline, and CD8, CD3 and granzyme B at follow-up
Our results indicate that CD4 expression and older age are adverse prognostic factors in wild-type NPM1 (show NPM1 Antibodies), FLT3 (show FLT3 Antibodies)-ITD-negative CN-AML (show RUNX1 Antibodies).
We investigated the prevalence, magnitude and phenotype of CTAg (show CTAG1B Antibodies)-specific T cells in the blood of patients with testicular germ cell tumors (TGCTs). CD8 (show CD8A Antibodies)(+) and CD4(+) T-cell responses against MAGE (show MAGEB10 Antibodies)-A family antigens were present in 44% (20/45) of patients' samples assayed by ex vivo IFN-gamma (show IFNG Antibodies) ELISPOT. Spontaneous T-cell immunity against CTAg (show CTAG1B Antibodies) proteins therefore develops in many patients with testicular cancer.
Depletion of the gamma2 or mu1A (AP1M1 (show AP1M1 Antibodies)) subunits of AP-1 (show FOSB Antibodies), but not of gamma1 (AP1G1 (show AP1G1 Antibodies)), precludes Nef-mediated lysosomal degradation of CD4.
findings provide a mechanistic explanation for previous observations that dimerization-defective Nef mutants fail to down-regulate CD4 and validate the Nef dimerization interface as a target site for antiretroviral drug development

Pig (Porcine) CD4 Molecule (CD4) interaction partners

The frequency and expression of a CD4 variant in microminipigs are described.
These data help clarify the regulatory mechanism of DNA methylation (show HELLS Antibodies) of the CD4 gene in non-immune cell response to virus replication.

Cow (Bovine) CD4 Molecule (CD4) interaction partners

These results suggest that CD4 plays a role in production traits as well as in immune function. The identified SNPs could be used as genetic markers for selection of dairy cows with improved fat percentage. We propose further studies of these SNPs in a larger population as well as further investigations of the function of this gene.
These results suggested that the SNPs in CD4 and STAT5b (show STAT5B Antibodies) may be potential genetic markers for SCS (show TWIST1 Antibodies) and milk/protein (show CSN2 Antibodies) yields selecting and warrant further functional research.
The DNA methylation (show HELLS Antibodies) level of the CD4 gene was strongly influenced by mastitis in Chinese Holstein cattle.
These findings revealed that despite the existence of a distinct bovine CD4(+)CD25 (show IL2RA Antibodies)(high) T cell population, which showed Foxp3 (show FOXP3 Antibodies) transcription/expression, natural regulatory activity did not reside in this cell population

Rhesus Monkey CD4 Molecule (CD4) interaction partners

The absence of CD4 T cells results in failure to produce antibodies that neutralize CD4-independent SIV Envs and CD4-pretriggered control SIV Envs.

Chimpanzee CD4 Molecule (CD4) interaction partners

study found noticeable variation in the first variable region V1 of CD4 and in intron six among the subspecies of chimpanzees.

CD4 Antigen Profile

Antigen Summary

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Alternative names and synonyms associated with CD4

CD4 molecule (CD4) antibody
carcinoembryonic antigen-related cell adhesion molecule 5 (LOC100125525) antibody
T-cell surface glycoprotein CD4 (cd4) antibody
CD4 antigen (Cd4) antibody
Cd4 molecule (Cd4) antibody
CD4 molecule (Cd4) antibody

cd4 antibody
CD4mut antibody
L3T4 antibody
Ly-4 antibody
p55 antibody
W3/25 antibody

Protein level used designations for anti-CD4 Molecule (CD4) Antibodies

CD4 antigen , T-cell surface glycoprotein CD4 , T-cell differentiation antigen L3T4 , T-cell surface antigen T4/Leu-3 , T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4) , CD4 antigen (p55) , CD4 receptor , W3/25 antigen , lymphocyte antigen CD4 , cell surface glycoprotein CD4

GENE ID	SPECIES
100016045	Monodelphis domestica
100125525	Oryzias latipes
778001	Takifugu rubripes
100286469	Salmo salar
12504	Mus musculus
920	Homo sapiens
24932	Rattus norvegicus
101790140	Anas platyrhynchos
493775	Felis catus
404704	Sus scrofa
395362	Gallus gallus
403931	Canis lupus familiaris
443509	Ovis aries
407098	Bos taurus
100734494	Cavia porcellus
100009152	Oryctolagus cuniculus
100126554	Meleagris gallopavo
713807	Macaca mulatta
450124	Pan troglodytes

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Show all anti-CD4 Molecule (CD4) Antibodies with Pubmed References