Browse our anti-CSK (CSK) Antibodies

Human C-Src tyrosine Kinase (CSK) interaction partners

1. Study indicated that MTHFR (show MTHFR Antibodies) rs1801133, FGF5 (show FGF5 Antibodies) rs16998073 and CSK rs1378942 were associated with increased the risk of obesity in the Chinese children.

2. These results identified a novel role for Csk as a host tyrosine kinase (show TXK Antibodies) involved in dengue virus replication.

3. Domain interactions of C-terminal Src Kinase determined through NMR spectroscopy with segmental isotope labeling

4. Data suggest that myristoylation of Src kinase is essential to facilitate Src (show SRC Antibodies)-induced and high-fat diet-accelerated prostatic tumor progression; targeting Src kinase myristoylation, which is required for Src kinase association at cellular membrane, blocks dietary fat-accelerated tumorigenesis.

5. Linear mixed-effect regressions showed significant association between rs1378942 in CSK and systolic blood pressure (beta = 0.98+/-0.46, P = 3.4x10-2). The child genotype scores for diastolic and systolic blood pressure were not associated in children.

6. H2O2-induced Csk translocation to the plasma membrane leads to phosphorylation of Src at the tyrosine 530 residue resulting in a reduction of ERK1/2 phosphorylation.

7. Data suggest that as a natural inhibitor of c-Src kinase, naringin could be an effective candidate for the treatment of melanoma.

8. deregulation of the Pragmin-Csk axis may induce aberrant cell migration that contributes to tumor invasion and metastasis

9. Our results do not support association between PTPN22 (show PTPN22 Antibodies)/CSK and Henoch-Schonlein purpura

10. Results identify CSK downregulation as a principal driver of SRC (show SRC Antibodies) activation and castration resistance.

Mouse (Murine) C-Src tyrosine Kinase (CSK) interaction partners

1. Our results have uncovered a previously unknown role of c-Src tyrosine kinase in regulating interneuron function in the brain and identified a novel mechanism by which TASK-1 (show KCNK3 Antibodies) channels are activated in neurons.

2. in the absence of PAG, Csk becomes more associated with alternative partners; i.e., phosphatase PTPN22 and Dok adaptors. Combining PAG deficiency with PTPN22 or Dok adaptor deficiency further enhances effector T cell responses. Unlike PAG, Cbl ubiquitin ligases inhibit the activation of naive, but not of effector, T cells.

3. Csk is a causative gene in the 15q24 locus and regulates blood pressure through Src (show SRC Antibodies), and these findings provide a novel therapeutic target for the treatment of hypertension

4. Csk plays an important role, not only in basal signaling, but also in setting the T cell antigen receptor signaling threshold and affinity recognition.

5. SHIP1 (show INPP5D Antibodies) and Csk are part of the PSTPIP2 (show PSTPIP2 Antibodies)-dependent inhibitory network that prevents the development of autoinflammatory disease.

6. If Cbp enhances the interaction between c-Src and FAK, Cbp could promote c-Src function when lipid rafts are disrupted.

7. Suggest critical role of Cav1 in modulating cSrc activation, gap junction remodeling, and ventricular arrhythmias.

8. Differentiation of embryonic stem cells is driven by c-Src (show SRC Antibodies) is antagonized by c-Yes (show YES1 Antibodies).

9. critical role in preventing TCR signaling

10. It was concluded that c-Src (show SRC Antibodies) and NADPH oxidase (show NOX1 Antibodies) components are necessary for redox-mediated production of TNF-alpha (show TNF Antibodies) following liver ischemia-reperfusion and that hepatocytes play an important role in this process.

Cow (Bovine) C-Src tyrosine Kinase (CSK) interaction partners

1. Dok-4 (show DOK4 Antibodies) has a role as an anchoring molecule for the tyrosine kinase (show TYRO3 Antibodies) c-Src (show SRC Antibodies), and in turn as a regulator of TNF-alpha (show TNF Antibodies)-mediated ROS (show ROS1 Antibodies) production and NF-kappaB (show NFKB1 Antibodies) activation

2. Src (show SRC Antibodies) family tyrosine kinases play a central role of arginase and inducible nitric oxide synthase (show NOS2 Antibodies) in pulmonary artery endothelium.

3. Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells.