Browse our anti-ATP1A1 (ATP1A1) Antibodies

Human ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) interaction partners

1. Low ATP1A1 expression is associated with renal cell carcinoma (show MOK Antibodies).

2. These data suggest the role of beta-amyloid as a novel physiological regulator of Na,K-ATPase.

3. induction of a novel pathway (alpha1-AMPK (show PRKAA1 Antibodies)-ULK1 (show ULK1 Antibodies)) induces autophagy as a host-directed strategy for HCMV inhibition.IMPORTANCE

4. An antibody against the extracellular DR region (897-911) of Na(+)-K(+)-ATPase subunit alpha 1 disrupted the Na+-K+-ATPase/ROS (show ROS1 Antibodies) amplifier and protected cultured cardiomyocytes from ROS-induced i (show ROS1 Antibodies)njury.

5. Disruption of Ankyrin B (show ANK2 Antibodies) and Caveolin-1 (show CAV1 Antibodies) Interaction Sites Alters Na(+),K(+)-ATPase Membrane Diffusion

6. Mutations in ATP1A1 cause the excessive autonomous aldosterone secretion of Aldosterone-producing Adenomas.

7. Cardiotonic steroids activate NF-kappaB (show NFKB1 Antibodies) leading to proinflammatory cytokine production in primary macrophages through a signaling complex, including CD36 (show CD36 Antibodies), TLR4 (show TLR4 Antibodies), and Na/K-ATPase.

8. This study reports molecular dynamic simulations of the human NaK-ATPase alpha1 beta 1 isoform embedded into 1,2-oleoylphosphatidylcholine bilayer.

9. Data show that the expression of aquaporin (AQP) 1, AQP3, AQP5, epithelial Na+ channel (ENaC) and sodium potassium ATPase (Na-K-ATPase) are altered in patients with acute respiratory failure (ARF) due to diffuse alveolar damage (DAD), and the cause of DAD does not seem to influence the level of impairment of these channels.

10. Ouabain stimulates NKA (show TAC1 Antibodies) in renal proximal tubule cells through an angiotensin/AT1R (show AGTR1 Antibodies)-dependent mechanism and that this pathway contributes to cardiac glycoside associated hypertension.

Pig (Porcine) ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) interaction partners

1. This study determined the specificity of the interaction between the N-terminus of the alpha-subunit (show POLG Antibodies) of the Na+,K+-ATPase and the surrounding membrane.

2. The findings are consistent with previous studies that indicate a link between Na,K-ATPase activity and SFK signaling.

3. Uroguanylin (show GUCA2B Antibodies) modulates (Na++K+)ATPase in a proximal tubule cells via cGMP/protein kinase (show CDK7 Antibodies) G, cAMP/protein kinase A, and mTOR (show FRAP1 Antibodies) pathways.

4. Data indicate that magnesium fluoride, magnesium fluoride and Na,K-ATPase form a very stable complex in the E2 conformation.

5. Data indicate that Rb(+) can be occluded through Na(+)/K(+)-ATPase cycling mode that takes place in the absence of Na(+) ions.

6. Expression of mutant alpha1 Na/K-ATPase defective in conformational transition attenuates Src (show SRC Antibodies)-mediated signal transduction

7. re-arrangements of the Na+,K+-ATPase stabilized by cardiotonic steroids may affect protein-protein interactions within the intracellular signal transduction networks

8. Data indicate that the transmembrane domain of the Na+/K+ -ATPase in the E1 state is less exposed to the lipids than in E2.

9. The plasma membrane Na/K-ATPase-caveolin-1 (show CAV1 Antibodies) interaction may represent an important sensing mechanism by which the cells regulate the sterol regulatory element-binding protein (show CNBP Antibodies) pathway.

10. Investigations of K(+)-occlusion by the phosphoenzyme of Na(+),K(+)-ATPase from shark rectal gland and pig kidney by stopped-flow fluorimetry reveal major differences in the kinetics of the two enzymes.

Cow (Bovine) ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) interaction partners

1. Suggest ATP1A1 has a central role in the osmoregulatory response of nucleus pulposus cells.

2. The ATP1A1 gene polymorphism has potential as a marker for mastitis resistance in dairy cattle.

3. The polymorphisms within the coding region of bovine ATP1A1 gene, were analyzed.

4. ATP1A1 gene polymorphism has a role in heat tolerance traits in dairy cattle

Xenopus laevis ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) interaction partners

1. The C-terminal contacts of Xenopus Na,K-ATPase alpha-1 provide important stabilization of the occluded E1P(Na3) pump conformation, regardless of the route of Na ion entry into the binding pocket.

Rabbit ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) interaction partners

1. Na,K-ATPase interaction with magnesium ions

2. Altered localization of Na-K-ATPase as a result of transcriptional down-regulation of ankyrin-G (show ANK3 Antibodies) mediates the down-regulation of Na-K-ATPase activity during chronic intestinal inflammation.

3. Pb(2+) ions are able to confine the Na(+),K(+)-ATPase into a phosphorylated E(2) state.

Mouse (Murine) ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) interaction partners

1. An antibody against the extracellular DR region (897-911) of Na(+)-K(+)-ATPase subunit alpha 1 disrupted the Na+-K+-ATPase/ROS (show ROS1 Antibodies) amplifier and protected embryonic hearts in organ culture from ROS (show ROS1 Antibodies)-induced injury and apoptosis.

2. Cardiotonic steroids activate NF-kappaB (show NFKB1 Antibodies) leading to proinflammatory cytokine production in primary macrophages through a signaling complex, including CD36 (show CD36 Antibodies), TLR4 (show TLR4 Antibodies), and Na/K-ATPase.

3. Study identified the Na+/K+-ATPase alpha 1 and 3 subunits as receptors for the extracellular fragment of GPNMB that mediates activation of cellular signaling pathways and subsequent neuroprotective effects.

4. effects of endogenous acetylcholine on alveolar fluid clearance are likely mediated by Na,K-ATPase function through activation of muscarinic acetylcholine receptors on alveolar epithelia

5. Oxidized LDL-bound CD36 (show CD36 Antibodies) recruits an Na/K-ATPase-Lyn (show LYN Antibodies) complex in macrophages that promotes atherosclerosis.

6. TGFbeta1 (show TGFB1 Antibodies) is a powerful regulator of megakaryocytic Na+/K+ ATPase activity.

7. Inhibition of the Na+/K+-ATPase pathway in astrocytes leads to rearrangement of cytoskeleton.

8. Reduction of Na/K-ATPase affects cardiac remodeling and increases c-kit cell abundance in partial nephrectomized mice.

9. Enhanced Na+ entry did not alter Na,K-ATPase a1 mRNA level in tranfected mCDD cells. Post-transcriptional control of Na,K-ATPase abundance is effected by lysosomal degradation.

10. This coupling of astrocytic A2ARs to the regulation of glutamate (show GRIN1 Antibodies) transport through modulation of NKA (show TAC1 Antibodies)-alpha2 activity provides a novel mechanism linking neuronal activity to ion homeostasis controlling glutamatergic activity.

Guinea Pig ATPase, Na+/K+ Transporting, alpha 1 Polypeptide (ATP1A1) interaction partners

1. Data identify the K+-independent, ouabain-insensitive Na+-ATPase (show DNAH8 Antibodies) as a unique P-type ATPase (show ATP7A Antibodies).