ATP1A1 antibody (Ser23)

Catalog No. ABIN7179977

Product Details anti-ATP1A1 Antibody

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Binding Specificity: Ser23

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human ATP1alpha1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000, IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: Atp1a1 (ATP1A1 Products)

Synonyms: Atpa-1 antibody, BC010319 antibody, Nkaa1b antibody, K-ATPase antibody, Na+K+ATPase antibody, atp1a1 antibody, atp1a1a.1 antibody, atp1a1l1 antibody, atp[a]1B1 antibody, cb70 antibody, wu:fa03c03 antibody, wu:fb92h10 antibody, atp1a1l5 antibody, atp[a]1B2 antibody, cb707 antibody, wu:fj34g01 antibody, zgc:92351 antibody, ATPase Na+/K+ transporting subunit alpha 1 antibody, ATPase, Na+/K+ transporting, alpha 1 polypeptide antibody, ATPase Na+/K+ transporting subunit alpha 1 L homeolog antibody, ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 1 antibody, ATPase, Na+/K+ transporting, alpha 1b polypeptide antibody, ATP1A1 antibody, Atp1a1 antibody, atp1a1.L antibody, atp1a1a.1 antibody, atp1a1b antibody

Background:

Background: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Shull G.E., Biochemistry 25:8125-8132(1986).
Hara Y., J. Biochem. 102:43-58(1987).
Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).

Aliases: Atp1a1Sodium/potassium-transporting ATPase subunit alpha-1 antibody, Na(+)/K(+) ATPase alpha-1 subunit antibody, EC 7.2.2.13 antibody, Sodium pump subunit alpha-1 antibody

UniProt: P06685

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process