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anti-Human CREB1 Antibodies:
anti-Mouse (Murine) CREB1 Antibodies:
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Mouse (Murine) Polyclonal CREB1 Primary Antibody for IHC, WB - ABIN152614 : Johannessen, Delghandi, Moens: What turns CREB on? in Cellular signalling 2004 (PubMed) Show all 8 Pubmed References
Human Polyclonal CREB1 Primary Antibody for IP, WB - ABIN151873 : Shi, Venkataraman, Dodson, Mabb, LeBlanc, Tibbetts: Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed) Show all 8 Pubmed References
Human Polyclonal CREB1 Primary Antibody for IHC - ABIN965927 : Rosenfeld, Correia, Xing, Rener, Cheung: Structural studies of kinesin-nucleotide intermediates. in The Journal of biological chemistry 1997 (PubMed) Show all 5 Pubmed References
Human Monoclonal CREB1 Primary Antibody for WB - ABIN1944898 : Berkowitz, Gilman: Two distinct forms of active transcription factor CREB (cAMP response element binding protein). in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed) Show all 5 Pubmed References
Human Polyclonal CREB1 Primary Antibody for IHC - ABIN965926 : Garat, Fankell, Erickson, Reusch, Bauer, McMurtry, Klemm: Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells. in Molecular and cellular biology 2006 (PubMed) Show all 3 Pubmed References
Human CREB1 Primary Antibody for IHC - ABIN965924 : Rothem, Stark, Assaraf: Impaired CREB-1 phosphorylation in antifolate-resistant cell lines with down-regulation of the reduced folate carrier gene. in Molecular pharmacology 2004 (PubMed) Show all 3 Pubmed References
Human Monoclonal CREB1 Primary Antibody for ICC, IHC - ABIN969061 : Jansson, Ng, Fu, Depatie, Al Azzabi, Screaton: Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed) Show all 3 Pubmed References
Human CREB1 Primary Antibody for IHC - ABIN965925 : Xing, Kornhauser, Xia, Thiele, Greenberg: Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. in Molecular and cellular biology 1998 (PubMed) Show all 4 Pubmed References
Human Monoclonal CREB1 Primary Antibody for IF, IHC - ABIN965928 : Seo, Chung: CREB activates proteasomal degradation of DSCR1/RCAN1. in FEBS letters 2008 (PubMed) Show all 3 Pubmed References
Human Monoclonal CREB1 Primary Antibody for ICS - ABIN1177047 : Shaywitz, Greenberg: CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. in Annual review of biochemistry 2000 (PubMed)
CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.
The sequence of the CREB gene contains a 88 bp 5 (show HSPD1 Antibodies)' UTR (show UTS2R Antibodies), a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3 (show BST1 Antibodies)' UTR (show UTS2R Antibodies).
Data indicate increasing expression for CREB, ATF1 (show AFT1 Antibodies), and ATF3 (show ATF3 Antibodies) during gastrulation.
Results indicate CREB1 as a critical transcription factor of RRM2 (show RRM2 Antibodies) which promotes tumor aggressiveness, and imply a significant correlation between CREB1 and RRM2 (show RRM2 Antibodies) in CRC (show CALR Antibodies) specimens.
Study suggest that both p300 (show EP300 Antibodies) and CREB are required for the function integrity of HIF-1alpha (show HIF1A Antibodies) transcription machinery and subsequent angiogenesis, suggesting future studies to improve burn wound healing might be directed to optimization of the interaction between p300 (show EP300 Antibodies), CREB and HIF-1alpha (show HIF1A Antibodies).
These findings suggest that CREB1 may be a potential therapeutic target for the treatment of gastric cancer
YAP (show YAP1 Antibodies)/ TAZ (show TAZ Antibodies) pathways contribute to the proliferation/quiescence switch during colon cancer 5FU treatment according to the concerted regulation of Cyclin E1 (show CCNE1 Antibodies) and CREB
Data demonstrate that CREB is downregulated in glioma cells and is a direct target of miR (show MLXIP Antibodies)-433-3p. These findings indicate that CREB subsequently directly or indirectly modulates its target genes to control the cell growth and metastasis in glioma.
these studies demonstrate that transcription factors CREB and c-Myc (show MYC Antibodies) maintain the transcriptional activity of STING
GRK3 (show ADRBK2 Antibodies) is a new critical activator of neuroendocrine phenotypes and mediator of CREB activation in promoting neuroendocrine differentiation of prostate cancer cells.
miR (show MLXIP Antibodies)-150 is a novel Wnt (show WNT2 Antibodies) effector that may significantly enhance epithelial-mesenchymal transition of colorectal cancer cells by targeting the CREB signaling pathway
fMRI and genotyping data from a large human sample, together with previous evidence, support the view that CREB1-associated mechanisms modulate brain function and behavior during reward-based decision-making.
Knockdown of either HIF-1 (show HIF1A Antibodies) or CREB or both in hypoxia reduced the expression of hypoxia-response elements- and CRE-mediated gene expression, diminished cell proliferation and increased caspase-3 (show CASP3 Antibodies) activity.
analysis of the molecular mechanisms through which CBP stability is regulated by FBXL19 and USP14, which results in the modulation of chromatin remodeling and the expression of cytokine-encoding genes
the requirement of Creb1 for normal mammalian lung morphogenesis is not dependent upon its expression in lung epithelium or mesenchyme, nor its role in musculoskeletal development.
data provide persuasive evidence towards the distinct roles of CREB within the dorsal and ventral hippocampus separately in mediating select nicotine withdrawal phenotypes.
phosphorylation of CREB is downregulated in the Muller glia.
Data suggest that the upregulation of mitochondrial respiratory chain proteins played a partial role in the protection of PKA/CREB signaling.
Both CREB and deltaFosB play a role in the induction of this behavioural sensitization.
astrocytic IL-17A (show IL17A Antibodies) plays important roles in the maintenance of neuropathic pain through CaMKII (show CAMK2G Antibodies)/CREB signaling pathway in spinal cord.
LH induces MAPK3 (show MAPK3 Antibodies)/1 and Akt (show AKT1 Antibodies) activation, both of which are required for the CREB-promoted expression of EGF (show EGF Antibodies)-like factors in granulosa cells.
However, the mechanism that induces release of IL-6 (show IL6 Antibodies) from skeletal muscle cells remains unknown. Here we show that heat increases IL-6 (show IL6 Antibodies) in skeletal muscle cells through the transient receptor potential vannilloid 1, PKC (show PKC Antibodies), and cAMP response element-binding protein signal transduction pathway.
NFIL3 (show NFIL3 Antibodies) functions as an important regulator of glucose homeostasis in the liver by limiting CREB-mediated hepatic gluconeogenesis
Data indicate that Ser738/742-to-glutamate (show GRIN2A Antibodies) protein kinase D (show PRKD1 Antibodies) mutant increased AngII-induced CREB protein and activating transcription factor 2 (show ATF2 Antibodies) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (show STAR Antibodies) promoter.
SUMO-1 has a role in modifying cAMP-response element-binding protein CREB in prolonged hypoxia.
dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (show LYPLA1 Antibodies)
the p38-MAPK (show MAPK14 Antibodies)/CREB pathway plays a critical role in TNFalpha (show TNF Antibodies)-induced VCAM-1 (show VCAM1 Antibodies) expression
We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements
p38 MAPK (show MAPK14 Antibodies) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (show MAPK14 Antibodies) pathway mediates the phosphorylation of CREB.
modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
cAMP responsive element binding protein 1 , cAMP responsive element binding protein , cyclic AMP-responsive element-binding protein 1 , CREB-1 , active transcription factor CREB , cAMP-response element-binding protein-1 , cAMP-responsive element-binding protein 1 , transactivator protein , Y protein , cAMP response element binding protein 1 , cAMP response element-binding protein , cyclic AMP-responsive element binding protein, delta , cyclic AMP-responsive DNA-binding protein
