Browse our anti-CREB1 (CREB1) Antibodies

Silk Worm cAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

1. CREB is positively regulated by PKA and calcium-sensitive calcineurin and negatively by PKC.

2. The sequence of the CREB gene contains a 88 bp 5 (show HSPD1 Antibodies)' UTR (show UTS2R Antibodies), a 783 bp open reading frame encoding 261 amino acids and a 348 bp 3 (show BST1 Antibodies)' UTR (show UTS2R Antibodies).

Rabbit cAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

1. Data indicate increasing expression for CREB, ATF1 (show AFT1 Antibodies), and ATF3 (show ATF3 Antibodies) during gastrulation.

Human cAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

1. Via activation of cAMP/PKA/CREB pathway and upregulation of the downstream FtMt (show FTMT Antibodies) expression.

2. The mechanism of prostaglandin E2-induced transcriptional up-regulation of Oncostatin-M (show OSM Antibodies) by CREB and Sp1 (show PSG1 Antibodies) has been described.

3. The findings suggest that activation of TGR5 (show GPBAR1 Antibodies) promoted mitochondrial biogenesis in endothelial cells, which is mediated by the CREB/PGC (show PGC Antibodies)-1a signaling pathway.

4. High CREB expression is associated with esophageal squamous cell carcinoma.

5. CREB1 may activate the transcription of wtBRAF through directly binding to its promoter, increasing BRAF (show BRAF Antibodies) expression and regulating the cell proliferation, migration and invasion of endometriosis.

6. to explore genetic variations in CREB1 promoter region and determine whether these loci affect transcriptional activity and risk on type 2 diabetes (T2D). Three polymorphisms were identified and designated as MU1, MU2 (show AP2M1 Antibodies) and MU3 (show COMMD7 Antibodies), respectively. Genotypic distribution analysis revealed that MU1 genotypes presented similar distribution between T2D and healthy controls (P>0.05)

7. experiments mainly reveal that the CREB1 could affect glucose transport in glioma cells by regulating the expression of GLUT1 (show SLC2A1 Antibodies), which controlled the metabolism of glioma and affected the progression of glioma.

8. These data highlight a novel arrestin (show SAG Antibodies)-mediated modulation of CREB signalling, suggesting a reciprocal relationship between arrestin2 and arrestin3, wherein recruitment of arrestin3 restricts the ability of beta2AR (show ADRB2 Antibodies) to activate prolonged CREB phosphorylation by precluding recruitment of an arrestin2/Src (show SRC Antibodies)/p38 (show CRK Antibodies) complex.

9. The authors conclude that taurodeoxycholic acid-induced DNA damage may depend on the activation of TGR5 (show GPBAR1 Antibodies), CREB and NOX5 (show NOX5 Antibodies)-S. It is possible that in Barrett's patients bile acids may activate NOX5 (show NOX5 Antibodies)-S and increase reactive oxygen species (ROS (show ROS1 Antibodies)) production via activation of TGR5 (show GPBAR1 Antibodies) and CREB. NOX5 (show NOX5 Antibodies)-S-derived ROS (show ROS1 Antibodies) may cause DNA damage, thereby contributing to the progression from Barrett's esophagus to esophageal adenocarcinoma.

10. The mechanism of CBP (show CREBBP Antibodies)-CREB association via their pKID/KIX domains studied by molecular dynamics free energy simulations has been reported.

Mouse (Murine) cAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

1. this study shows that CREB is a critical regulator of dendritic cells during the germinal center response

2. FXR (show NR1H4 Antibodies) exerts its function in L cells through interacting with CREB, a crucial transcriptional regulator of cAMP-CREB signaling pathway, to inhibit its transcriptional activity. Targeting FXR (show NR1H4 Antibodies) to rescue GLP-1 (show GCG Antibodies) secretion may be a promising strategy for type II diabetes.

3. Antioxidative and Anti-Melanogenic Activities of Bamboo Stems (Phyllostachys nigra variety henosis) via PKA/CREB-Mediated MITF (show MITF Antibodies) Downregulation in B16F10 Melanoma Cells

4. Unexpectedly, although dispensable for FOXP3 (show FOXP3 Antibodies) expression and for the homeostasis and suppressive function of thymus-derived Treg cells, CREB negatively regulates the survival of TGF-beta (show TGFB1 Antibodies)-induced Treg cells, and deletion of CREB resulted in increased FOXP3 (show FOXP3 Antibodies)+ Treg cells in the intestine and protection in a colitis model

5. The absence of gut (show GUSB Antibodies) microbiota from birth was shown to be associated with decreased CREB expression, followed by decreases of protein kinase C beta (PRKCB (show PRKCB Antibodies)) and AMPA (show GRIA3 Antibodies) receptors expression, and an increase of phosphorylation CREB (pCREB) expression.

6. Findings suggest that cAMP response element binding protein -mediated hippoacampus structural plasticity is crucial for the role of 5-HT1a receptor (show CC2D1A Antibodies) in modulating anxiety-related behaviors.

7. Significant CREB activation in almost the whole amygdala and hippocampus was observed after unconditioned stimulus-retrieval, but conditioned stimulus-retrieval only stimulated CREB activation in the lateral amygdala and the CA3 (show CA3 Antibodies) of hippocampus. In addition, propranolol, a beta (show SUCLA2 Antibodies)-adrenergic receptor antagonist, treatment suppressed memory retrieval-induced CREB activation.

8. Curc-mPEG454 reverses HFD-induced hepatic steatosis via the activation of CREB inhibition.

9. Neuron-specific, adult-deletion of CREB1 alters hippocampal structures and causes neuropathological changes resembling aging brain.

10. analysis of the molecular mechanisms through which CBP stability is regulated by FBXL19 and USP14, which results in the modulation of chromatin remodeling and the expression of cytokine-encoding genes

Cow (Bovine) cAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

1. Data indicate that Ser738/742-to-glutamate (show GRIN2A Antibodies) protein kinase D (show PRKD1 Antibodies) mutant increased AngII-induced CREB protein and activating transcription factor 2 (show ATF2 Antibodies) phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein (show STAR Antibodies) promoter.

2. SUMO-1 has a role in modifying cAMP-response element-binding protein CREB in prolonged hypoxia.

3. dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2 (show LYPLA1 Antibodies)

4. the p38-MAPK (show MAPK14 Antibodies)/CREB pathway plays a critical role in TNFalpha (show TNF Antibodies)-induced VCAM-1 (show VCAM1 Antibodies) expression

Xenopus laevis cAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

1. We found several conserved cis elements in the frog CRF genes including a cAMP response element (CRE), activator protein 1 binding sites, and glucocorticoid response elements

2. p38 MAPK (show MAPK14 Antibodies) and CREB function along the dorsal-ventral axis in mesoderm patterning. The phosphorylated form of CREB (S133) is distributed in a gradient along the dorsal-ventral mesoderm axis and the p38 MAPK (show MAPK14 Antibodies) pathway mediates the phosphorylation of CREB.

Zebrafish cAMP Responsive Element Binding Protein 1 (CREB1) interaction partners

1. modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning