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anti-Human IRX1 Antibodies:
anti-Mouse (Murine) IRX1 Antibodies:
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Human Polyclonal IRX1 Primary Antibody for ELISA, WB - ABIN566348
Zougman, Mann, Wisniewski: Identification and characterization of a novel ubiquitous nucleolar protein 'NARR' encoded by a gene overlapping the rab34 oncogene. in Nucleic acids research 2011
Show all 3 Pubmed References
A total of three nonsynonymous mutations (p.Gln240Glu, p.Ser298Asn and p.Ala381Glu) of the IRX1 (show IRX3 Antibodies) gene were verified in 215 nonsyndromic congenital heart disease patients.
this is the first genome-wide association study of Rheumatoid Factor positivity in Rheumatoid Arthritis. Variation at the IRX1 (show IRX3 Antibodies) locus on chromosome 5p15.3 is associated with the presence of Rheumatoid Factor. Our findings indicate that IRX1 (show IRX3 Antibodies) and HLA-DRB1 (show HLA-DRB1 Antibodies) are the strongest genetic factors for Rheumatoid Factor production in Rheumatoid Arthritis.
In osteosarcoma cells and lines, IRX1 (show IRX3 Antibodies) overexpression was associated with hypomethylation of its own promoter. Experimental modulation in cell lines altered migration, invasion, and resistance to anoikis in vitro, and influenced lung metastasis in mice.
Findings suggest that methylation-associated down-regulation of EBF3 (show MAPRE3 Antibodies) and IRX1 (show IRX3 Antibodies) genes may play an important role in a pathogenic effect of TGF-beta (show TGFB1 Antibodies) on RASFs.
Helicobacter pylori infection contributes to IRX1 (show IRX3 Antibodies) promoter methylation in gastric mucosa.
enforcing IRX1 (show IRX3 Antibodies) expression effectively suppresses peritoneal spreading and pulmonary metastasis via anti-angiogenesis and anti-VM mechanisms, in addition to previously found cell growth and invasion.
Homeobox (show Lbx1 Antibodies) gene IRX1 (show IRX3 Antibodies) is a tumor suppressor gene in gastric carcinoma.
Results verify IRX1 (show IRX3 Antibodies), EBF3 (show MAPRE3 Antibodies), SLC5A8 (show SLC5A8 Antibodies), SEPT9 (show SEPT9 Antibodies), and FUSSEL18 (show SKOR2 Antibodies) as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1 (show IRX3 Antibodies), EBF3 (show MAPRE3 Antibodies), SLC5A8 (show SLC5A8 Antibodies), and SEPT9 (show SEPT9 Antibodies).
Frequent methylation of IRX1 (show IRX3 Antibodies) gene is associated with head and neck squamous cell carcinoma
Irx1 regulates Foxj1 (show FOXJ1 Antibodies) and Sox9 (show SOX9 Antibodies) to control cell differentiation during development.
This homeobox protein (show HOXA1 Antibodies) is expressed during early lung development.
This homeobox protein (show HOXA1 Antibodies) is expressed during digit development and is an early marker for this development.
Observations suggest that Irx2 (show IRX2 Antibodies) functions downstream of irx1a to control shh (show SHH Antibodies) expression in the retina. Study proposed a novel transcriptional cascade of ath5 (show ATOH7 Antibodies)-irx1a-irx2a in the regulation of hedgehog (show SHH Antibodies) waves during vertebrate retinal development.
Data revealed that expression of DNA binding inhibitor 3 (show PPP1R11 Antibodies), early B cell factor 2 (show EBF2 Antibodies), Ebf3 (show EBF3 Antibodies), Iroquois related homeobox 1, Kruppel-like factor 7 , mab-21-like 1 (show MAB21L1 Antibodies) , fatty acid binding protein 7 (show FABP7 Antibodies) and stathmin-like 4 (show STMN4 Antibodies),were enriched in the diencephalon of zebrafish.
Our results reveal a role for Iroquois genes in controlling hedgehog (show SHH Antibodies) expression during vertebrate retinogenesis.
irx1a is not required for the initial specification but it is required for the complete differentiation of 5HT (show DDC Antibodies) neurons
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13.
homeodomain protein IRXA1
, iroquois homeobox protein 1
, iroquois-class homeodomain protein IRX-1
, iroquois homologue-1
, iroquois homeobox 1
, iroquois-class homeodomain protein irx-1
, Iroquois related homeobox 1
, Iroquois homeobox protein 1-A
, homeobox Iro protein
, iroquois-class homeodomain protein irx-1-A
, LOW QUALITY PROTEIN: iroquois-class homeodomain protein IRX-1
, Iroquois homeobox protein 1-B
, iroquois-class homeodomain protein irx-1-B