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VHL Proteins

7 results:

Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-172) protein (GST tag) Protein

VHL Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB
Pubmed 1
Catalog No. ABIN6923012
$498.33
Plus shipping costs $45.00 and $24.00 dry ice
2 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-213) protein (His tag) Protein

Crystallography grade VHL Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3075417
$7,594.15
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 50 Business Days
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 6-175) protein (T7 tag,His tag) Protein

VHL Origin: Rat Host: Escherichia coli (E. coli) Recombinant ≥ 95 % ELISA, IP, SDS, WB
Catalog No. ABIN6237605
$460.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 12 to 15 Business Days
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

VHL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2735257
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-154) protein (His tag) Protein

VHL Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN806963
$313.85
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) Protein Protein

VHL Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Catalog No. ABIN2132533
$409.46
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-219) protein (His tag) Protein

VHL Origin: Dog Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1634750
$2,544.67
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days
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  • Type Protein
    • Protein
  • Target Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL)
    • Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • SARS-CoV-2 Spike
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 Homolog (S. Cerevisiae) (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Epidermal Growth Factor Receptor (EGFR)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Adenosylhomocysteinase (AHCY)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • SARS-CoV-2 Spike S1
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Thymidine Kinase 1, Soluble (TK1)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Programmed Cell Death 1 (PDCD1)
    • Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Immunoprecipitation (IP)
    • Protein Interaction (PI)
    • Standard (STD)
    • Crystallization (Crys)
  • Reactivity
    • Human
    • Dog
    • Rat
  • Cited in publications
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Insect Cells
    • Wheat germ
    • Yeast
  • Binding Specificity
    • AA 1-154
    • AA 1-172
    • AA 1-213
    • AA 1-219
    • AA 6-175
    • Transcript Variant 1
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • T7 tag,His tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Crystallography grade

VHL Protein Profile

Protein Summary

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with VHL

  • von Hippel-Lindau tumor suppressor (VHL) antibody
  • von Hippel-Lindau (Vhl) antibody
  • von Hippel-Lindau tumor suppressor (vhl) antibody
  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (VHL) antibody
  • von Hippel-Lindau disease tumor suppressor (CpipJ_CPIJ009992) antibody
  • von Hippel-Lindau tumor suppressor (Vhl) antibody
  • BcDNA:RH61560 antibody
  • CG13221 antibody
  • d-vhl antibody
  • Dmel\\CG13221 antibody
  • dmVHL antibody
  • dVHL antibody
  • hrca1 antibody
  • pVHL antibody
  • rca1 antibody
  • vhl antibody
  • vhl1 antibody
  • Vhlh antibody
  • zgc:158722 antibody

Protein level used designations for VHL

elongin binding protein , protein G7 , von Hippel-Lindau disease tumor suppressor , CG13221-PA , CG13221-PB , Vhl-PA , Vhl-PB , von hippel lindau , von hippel lindau protein , pVHL , von Hippel-Lindau tumor suppressor , von Hippel-Lindau syndrome homolog , von Hippel-Lindau syndrome protein homolog , Von Hippel-Lindau disease tumor suppressor

GENE ID SPECIES
7428 Homo sapiens
53433 Drosophila melanogaster
100173372 Pongo abelii
494000 Canis lupus familiaris
416117 Gallus gallus
549121 Xenopus (Silurana) tropicalis
791202 Danio rerio
540957 Bos taurus
6042662 Culex quinquefasciatus
22346 Mus musculus
24874 Rattus norvegicus
100380306 Salmo salar

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