VHL Proteins
9 Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) Proteins from 6 manufacturers are available on www.antibodies-online.com.
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Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-172) protein (GST tag) Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-213) protein (His tag) Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) protein (His tag) Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 6-175) protein (T7 tag,His tag) Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) Protein Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-154) protein (His tag) Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) Protein Protein
Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL) (AA 1-219) protein (His tag) Protein
VHL Protein Profile
Protein Summary
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alternative names and synonyms associated with VHL
- von Hippel-Lindau tumor suppressor (VHL) antibody
- von Hippel-Lindau (Vhl) antibody
- von Hippel-Lindau tumor suppressor (vhl) antibody
- von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (VHL) antibody
- von Hippel-Lindau disease tumor suppressor (CpipJ_CPIJ009992) antibody
- von Hippel-Lindau tumor suppressor (Vhl) antibody
- BcDNA:RH61560 antibody
- CG13221 antibody
- d-vhl antibody
- Dmel\\CG13221 antibody
- dmVHL antibody
- dVHL antibody
- hrca1 antibody
- pVHL antibody
- rca1 antibody
- vhl antibody
- vhl1 antibody
- Vhlh antibody
- zgc:158722 antibody
Protein level used designations for VHL
elongin binding protein , protein G7 , von Hippel-Lindau disease tumor suppressor , CG13221-PA , CG13221-PB , Vhl-PA , Vhl-PB , von hippel lindau , von hippel lindau protein , pVHL , von Hippel-Lindau tumor suppressor , von Hippel-Lindau syndrome homolog , von Hippel-Lindau syndrome protein homolog , Von Hippel-Lindau disease tumor suppressor
GENE ID | SPECIES |
---|---|
7428 | Homo sapiens |
53433 | Drosophila melanogaster |
100173372 | Pongo abelii |
494000 | Canis lupus familiaris |
416117 | Gallus gallus |
549121 | Xenopus (Silurana) tropicalis |
791202 | Danio rerio |
540957 | Bos taurus |
6042662 | Culex quinquefasciatus |
22346 | Mus musculus |
24874 | Rattus norvegicus |
100380306 | Salmo salar |
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