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Browse our anti-KREMEN1 (KREMEN1) Antibodies

Full name:: anti-Kringle Containing Transmembrane Protein 1 Antibodies (KREMEN1)

On www.antibodies-online.com are 82 Kringle Containing Transmembrane Protein 1 (KREMEN1) Antibodies from 19 different suppliers available. Additionally we are shipping KREMEN1 Proteins (11) and KREMEN1 Kits (10) and many more products for this protein. A total of 110 KREMEN1 products are currently listed.

Synonyms:: AV002070, kremem1, Kremen, KREMEN1, Krm1, si:ct737139.1, si:dkeyp-7c9.1

list all antibodies	Gene Name	GeneID	UniProt
	KREMEN1	83999	Q96MU8
	KREMEN1	84035	Q99N43
	KREMEN1	114107	Q924S4
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Most Popular Reactivities for anti-KREMEN1 (KREMEN1) Antibodies

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anti-Human KREMEN1 Antibodies:

anti-Mouse (Murine) KREMEN1 Antibodies:

18 WB Antibodies

anti-Rat (Rattus) KREMEN1 Antibodies:

16 WB Antibodies

All available anti-KREMEN1 Antibodies

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Relevant Pathways for anti-KREMEN1 Antibodies

WNT Signaling

More product categories related to KREMEN1 Antibody

Top referenced anti-KREMEN1 Antibodies

Human Polyclonal KREMEN1 Primary Antibody for ELISA, WB - ABIN543953 : Nakamura, Aoki, Kitajima, Takahashi, Matsumoto, Nakamura: Molecular cloning and characterization of Kremen, a novel kringle-containing transmembrane protein. in Biochimica et biophysica acta 2001 (PubMed)
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Human Polyclonal KREMEN1 Primary Antibody for IHC (p), ELISA - ABIN542856 : Mao, Wu, Davidson, Marhold, Li, Mechler, Delius, Hoppe, Stannek, Walter, Glinka, Niehrs: Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. in Nature 2002 (PubMed)
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Mouse (Murine) Polyclonal KREMEN1 Primary Antibody for CyTOF, FACS - ABIN4899514 : Diarra, Stolina, Polzer, Zwerina, Ominsky, Dwyer, Korb, Smolen, Hoffmann, Scheinecker, van der Heide, Landewe, Lacey, Richards, Schett: Dickkopf-1 is a master regulator of joint remodeling. in Nature medicine 2007 (PubMed)
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More Antibodies against KREMEN1 Interaction Partners

Human Kringle Containing Transmembrane Protein 1 (KREMEN1) interaction partners

Dkk4 CRD2 mediates high-affinity binding to both the E1E2 region of low-density lipoprotein receptor-related protein 6 (LRP6 E1E2) and the Kremen1 (Krm1) extracellular domain.
Structure of the dual-mode Wnt regulator Kremen1 and insight into ternary complex formation with LRP6 and DKK1 have been presented.
Ectodermal dysplasia including oligodontia is due to homozygosity for KREMEN1 p.F209S (c.626 T>C).
Kremen1 has a pro-apoptotic activity that is decreased upon Dkk1 binding or by cancer mutations.
Six Dkk-1, three Sost, one Kremen-1 and 10 LRP-5 polymorphisms were significantly associated with radiological progression of rheumatoid arthritis joint destruction.
The mRNA expression levels of DKK-1 binding receptor LRP5/6 and Krm1/2 in SCs from patients with MM were significantly higher than those in myeloma cells and in SCs from healthy donors.
This study demonstrated that a representative tSNP of KREMEN1 might modulate the risk of schizophrenia in the Japanese population.
Kremen may not be essential for Dkk1-mediated Wnt antagonism and Kremen may only play a role when cells express a high level of LRP5/6
Functional characterization of related Kremen proteins in mouse.

Mouse (Murine) Kringle Containing Transmembrane Protein 1 (KREMEN1) interaction partners

Kremen1 is expressed in prosensory cells during cochlear developme
Kremen1 has a pro-apoptotic activity that is decreased upon Dkk1 binding
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling
Dkk1 and Kremen1 play roles in blastocyst activation and uterine receptivity during the window of implantation.
Kremen may not be essential for Dkk1-mediated Wnt antagonism and Kremen may only play a role when cells express a high level of LRP5/6
This study provides the first genetic evidence for a functional interaction of Kremen proteins with Dkk1 as negative regulators of Wnt/beta-catenin signaling.

Zebrafish Kringle Containing Transmembrane Protein 1 (KREMEN1) interaction partners

Data show that fish lacking Kremen1 protein develop more hair cells per neuromast compared to wild type fish.
Kremen1 modulates Wnt activity by restricting the range of secreted Dkk proteins during collective cell migration in the posterior lateral line primordium

KREMEN1 Antigen Profile

Antigen Summary

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Alternative names and synonyms associated with KREMEN1

kringle containing transmembrane protein 1 (KREMEN1) antibody
kringle containing transmembrane protein 1 (kremen1) antibody
kringle containing transmembrane protein 1 (Kremen1) antibody
kringle containing transmembrane protein 1 S homeolog (kremen1.S) antibody

AV002070 antibody
kremem1 antibody
Kremen antibody
KREMEN1 antibody
Krm1 antibody
si:ct737139.1 antibody
si:dkeyp-7c9.1 antibody

Protein level used designations for KREMEN1

kringle containing transmembrane protein 1 , kringle-containing transmembrane protein 1 , kremen 1 , kremen protein 1-like , dickkopf receptor , kremen protein 1 , kringle domain-containing transmembrane protein 1 , kringle-coding gene marking the eye and the nose , kringle-containing protein marking the eye and the nose , krm1

GENE ID	SPECIES
416920	Gallus gallus
486340	Canis lupus familiaris
524357	Bos taurus
748246	Pan troglodytes
100064476	Equus caballus
100144698	Xenopus (Silurana) tropicalis
100407744	Callithrix jacchus
100438112	Pongo abelii
100470669	Ailuropoda melanoleuca
100543996	Meleagris gallopavo
100595234	Nomascus leucogenys
83999	Homo sapiens
84035	Mus musculus
398249	Xenopus laevis
114107	Rattus norvegicus
100141352	Danio rerio

Selected quality suppliers for anti-KREMEN1 (KREMEN1) Antibodies

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Show all anti-Kringle Containing Transmembrane Protein 1 (KREMEN1) Antibodies with Pubmed References