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5'-Nucleotidase, Cytosolic II Proteins (NT5C2)

NT5C2 encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. Additionally we are shipping 5'-Nucleotidase, Cytosolic II Antibodies (52) and 5'-Nucleotidase, Cytosolic II Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NT5C2 100363253  
NT5C2 22978 P49902
NT5C2 76952 Q3V1L4
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Top 5'-Nucleotidase, Cytosolic II Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$413.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

NT5C2 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)
Human , ,
,
Mouse (Murine)

Top referenced 5'-Nucleotidase, Cytosolic II Proteins

  1. Human NT5C2 Protein expressed in Escherichia coli (E. coli) - ABIN667570 : Oka, Matsumoto, Hosokawa, Inoue: Molecular cloning of human cytosolic purine 5'-nucleotidase. in Biochemical and biophysical research communications 1995 (PubMed)
    Show all 2 references for ABIN667570

More Proteins for 5'-Nucleotidase, Cytosolic II (NT5C2) Interaction Partners

Human 5'-Nucleotidase, Cytosolic II (NT5C2) interaction partners

  1. Leukemia Relapse-Associated Mutation of NT5C2 Gene is Rare in de Novo Acute Leukemias and Solid Tumors.

  2. cN-II co-immunoprecipitated both with wild type Ipaf (show NLRC4 Proteins) and its LRR domain after transfection with corresponding expression vectors, but not with Ipaf (show NLRC4 Proteins) lacking the LRR domain.

  3. Data indicate that type II cytosolic 5'-nucleotidase (show NT5E Proteins) (cN-II) exerts a role in nucleotide and drug metabolism and regulating cell survival.

  4. Four novel body mass index-associated loci near the KCNQ1 (show KCNQ1 Proteins)(rs2237892), ALDH2 (show ALDH2 Proteins)/MYL2 (show MYL2 Proteins) (rs671, rs12229654), ITIH4 (show ITIH4 Proteins) (rs2535633) and NT5C2 (rs11191580) genes are identified in East Asian-ancestry populations.

  5. These results suggest that mutations in NT5C2 are associated with the outgrowth of drug-resistant clones in acute lymphoblastic leukemia

  6. results highlight the prominent role of relapse-specific mutations in NT5C2 as a mechanism of resistance to 6-Mercaptopurine and a genetic driver of relapse in acute lymphoblastic leukemia

  7. analysis of Drosophila and human 7-methyl GMP-specific nucleotidases

  8. Polymorphisms in the CYP17A1 (show CYP17A1 Proteins) and NT5C2 genes influence a reduction in both visceral and subcutaneous fat mass in Japanese women.

  9. seven high-resolution structures of human cN-II, including a ligand-free form and complexes with various substrates and effectors, were presented.

  10. cN-II has a role in protecting against progression of non-small cell lung cancer

Cow (Bovine) 5'-Nucleotidase, Cytosolic II (NT5C2) interaction partners

  1. mutated three residues that mediate interaction in the first activation site (R144, N154, I152) and three in the second (F127, M436 and H428), and found that ApA and ADP interact with the same site, but the sites for ATP and BPG remain uncertain

5'-Nucleotidase, Cytosolic II (NT5C2) Protein Profile

Protein Summary

This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides.

Gene names and symbols associated with NT5C2

  • 5'-nucleotidase, cytosolic IIa (nt5c2a)
  • 5'-nucleotidase, cytosolic II (NT5C2)
  • 5'-nucleotidase, cytosolic II (nt5c2)
  • 5'-nucleotidase, cytosolic II (surE2)
  • 5'-nucleotidase, cytosolic II (LOC100363253)
  • 5'-nucleotidase, cytosolic II (Nt5c2)
  • 2010002I23Rik protein
  • cN-II protein
  • CnII protein
  • ENSMUSG00000025039 protein
  • Gm9751 protein
  • Gmp protein
  • Nt5b protein
  • NT5C2 protein
  • Pnt5 protein
  • wu:fc36f11 protein
  • wu:fc45b10 protein

Protein level used designations for NT5C2

5'-nucleotidase, cytosolic II , fc36f11 , cytosolic 5'-nucleotidase II , cytosolic purine 5'-nucleotidase , cytosolic purine 5'-nucleotidase-like , 5'-nucleotidase (purine), cytosolic type B , IMP-specific 5'-NT , purine 5' nucleotidase , 5'-nucleotidase cytosolic II , cytosolic IMP/GMP-specific 5'-nucleotidase

GENE ID SPECIES
324845 Danio rerio
450706 Pan troglodytes
548490 Xenopus (Silurana) tropicalis
714292 Macaca mulatta
5808749 Sorangium cellulosum So ce56
100172749 Pongo abelii
100363253 Rattus norvegicus
100402763 Callithrix jacchus
22978 Homo sapiens
76952 Mus musculus
294016 Rattus norvegicus
477809 Canis lupus familiaris
281951 Bos taurus
423871 Gallus gallus
444729 Xenopus laevis
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