ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 Proteins (ADAMTS7)

The protein encoded by ADAMTS7 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Additionally we are shipping ADAMTS7 Antibodies (55) and ADAMTS7 Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADAMTS7 108153  
ADAMTS7 11173 Q9UKP4
ADAMTS7 315879 Q1EHB3
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Top ADAMTS7 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 13 to 16 Days
$720.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$640.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$845.63
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days
$914.38
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$928.13
Details

ADAMTS7 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , ,
,
Rat (Rattus)

More Proteins for ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7) Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7) interaction partners

  1. Therefore, these data provided the in vivo evidence, suggesting that ADAMTS-7 may play an important role in the pathogenesis of inflammatory arthritis.

  2. Mice lacking Adamts7, Ldlr, Apoe had less lesion formation in aortas and aortic roots vs controls and less neointimal formation after femoral wire injury. Adamts7 expression was induced by injury and hyperlipidemia.

  3. Adamts-7 deficiency substantially ameliorated neointima formation in mice at days 14 and 28 after injury. ADAMTS-7 inhibited both endothelial cell proliferation and migration.

  4. ADAMTS-7 and TNF-alpha (show TNF Proteins) form a positive feedback loop in the regulation of cartilage degradation and osteoarthritis progression.

  5. ADAMTS7B has a domain organization with a total of eight thrombospondin type 1 repeats in its ancillary domain. Of these, seven are arranged in two distinct clusters that are separated by a mucin (show SLC13A2 Proteins) domain

  6. Findings demonstrate that ADAMTS-7, a direct target of PTHrP signaling, negatively regulates endochondral bone formation by associating with and inactivating GEP (show GRN Proteins) chondrogenic growth factor.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7) interaction partners

  1. Allelic variation that associates with reduced ADAMTS7 expression confers stronger coronary heart disease protection in never-smokers than in ever-smokers.

  2. During inflammatory conditions, AP-1 (show FOSB Proteins) and Sp1 (show PSG1 Proteins) sustained the expression of ADAMTS7, and ADAMTS7 sustained the expression of catabolic genes in nucleus pulposus cells

  3. ADAMTS7 and LPA single nucleotide polymorphisms are related to a 24-h ambulatory systolic-diastolic pressure regression index.

  4. Expression of miR (show MLXIP Proteins)-26a and miR (show MLXIP Proteins)-29a was significantly down regulated in leukoplakia and cancer tissues but up regulated in lichen planus tissues. Expression of target genes such as, ADAMTS7, ATP1B1 (show ATP1B1 Proteins), COL4A2 (show COL4a2 Proteins), CPEB3 (show CPEB3 Proteins), CDK6 (show CDK6 Proteins), DNMT3a (show DNMT3A Proteins) and PI3KR1 was significantly down regulated in at least two of three disease types with respect to normal tissues.

  5. Our results indicate the presence of ADAMTS-7 in human NP cells and imply its potential role in disc degeneration.

  6. The main contribution of this study is the proposal of a pharmacophore for ADAMTS7.

  7. The significant associations observed between this coding variant in ADAMTS7 and the risk of CAD development.

  8. Logistic regression analysis indicated that the association between ADAMTS-7 and heart failure after AMI (show CFD Proteins) was independent from traditional cardiovascular risk factors and other biomarkers

  9. Data conclude that ADAMTS-7 level appears to be positively associated with expression of TNF-alpha (show TNF Proteins) and Phospho-NF-kappaB (show NFKB1 Proteins) P65 (show GORASP1 Proteins) in cartilage, which may imply its association with cartilage destruction of ONFH.

  10. ADAMTS7 localized to cells having smooth muscle cell markers in human coronary artery disease lesions. Cultured vascular smooth muscle cells had ADAMTS7 at the cytoplasm and cell membrane, where it colocalized with markers of podosomes.

ADAMTS7 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs.

Gene names and symbols associated with ADAMTS7

  • ADAM metallopeptidase with thrombospondin type 1 motif, 7 (ADAMTS7)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 (Adamts7)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 7 (Adamts7)
  • ADAM-TS7 protein
  • ADAM-TS 7 protein
  • ADAMTS-7 protein
  • ADAMTS7B protein
  • COMPase protein

Protein level used designations for ADAMTS7

ADAM metallopeptidase with thrombospondin type 1 motif, 7 , A disintegrin and metalloproteinase with thrombospondin motifs 7 , ADAM-TS 7 , ADAMTS-7 , COMPase , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 , metalloprotease , a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein , ADAM-TS7 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7

GENE ID SPECIES
100026396 Monodelphis domestica
108153 Mus musculus
11173 Homo sapiens
100340872 Oryctolagus cuniculus
315879 Rattus norvegicus
504694 Bos taurus
100728771 Cavia porcellus
100154398 Sus scrofa
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