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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Additionally we are shipping ATG4 Autophagy Related 4 Homolog A (S. Cerevisiae) Proteins (7) and many more products for this protein.
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Human Polyclonal ATG4A Primary Antibody for IHC (p), WB - ABIN1882158
Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005
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Human Polyclonal ATG4A Primary Antibody for IHC (p), WB - ABIN388491
Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005
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Human Polyclonal ATG4A Primary Antibody for EIA, IHC (p) - ABIN1449633
Greenberg: Degrade or die: a dual function for autophagy in the plant immune response. in Developmental cell 2005
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Human Polyclonal ATG4A Primary Antibody for IHC (p), WB - ABIN388493
Levine: Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. in Cell 2005
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Human Polyclonal ATG4A Primary Antibody for ELISA, IHC - ABIN4282098
Scherz-Shouval, Sagiv, Shorer, Elazar: The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A. in The Journal of biological chemistry 2003
Cow (Bovine) Polyclonal ATG4A Primary Antibody for WB - ABIN2775540
Scherz-Shouval, Shvets, Fass, Shorer, Gil, Elazar: Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. in The EMBO journal 2007
Human Polyclonal ATG4A Primary Antibody for IF, IHC - ABIN1534812
Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: The DNA sequence of the human X chromosome. ... in Nature 2005
We conclude that miR (show MLXIP Antibodies)-24-3p regulates autophagy by targeting ATG4A
The autophagy regulator ATG4A was found to be essential for the maintenance of a sub-population with cancer stem cell properties and to regulate breast cancer cell tumourigenicity.
The demonstration that expression of ATG4A in cells increased stem properties provided an indication of its biological function. Hypomethylation of ATG4A and HIST1H2BN in ovarian tumor-initiating cells predicts poor prognosis for ovarian cancer patients.
The actions of ATG4 family members (particularly ATG4B (show ATG4B Antibodies)) are required for the control of autophagosome fusion with late, degradative compartments in differentiating human erythroblasts.
statistical analysis of APG4A gene confirmed the characterisation of each protein-coding gene present in human genome Xq22.1
Atg4B (show ATG4B Antibodies) possessed the broadest spectrum against all substrates, followed by Atg4A for ATG8 (show GABARAPL2 Antibodies) substrates
HsApg4A cleaves the COOH terminus of GATE-16 (show GABARAPL2 Antibodies)
The cysteine protease (show CTSB Antibodies) HsAtg4 is identified as a direct target for oxidation by hydrogen peroxide, and a cysteine residue located near the HsAtg4 catalytic site as critical for this regulation.
MiR (show MLXIP Antibodies)-144 inhibits the autophagy-related gene Atg4a expression in Mycobacterium tuberculosis infection.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
ATG4 autophagy related 4 homolog A
, autophagy-related protein 4 homolog A
, cysteine protease ATG4A
, autophagy-related cysteine endopeptidase 2
, Cysteine protease ATG4A
, autophagy-related cysteine endopeptidase 2A
, APG4 autophagy 4 homolog A
, AUT-like 2 cysteine endopeptidase
, AUT-like 2, cysteine endopeptidase
, autophagin 2
, APG4 (ATG4) autophagy-related homolog A
, autophagy 4 homolog A
, autophagy-related 4A
, cysteine protease APG4A
, autophagy related 4 homolog A
, autophagy related 4A, cysteine peptidase
, uncharacterized protein LOC678769