ATG4A antibody (AA 289-398)

Catalog No. ABIN3023409

This Rabbit Polyclonal antibody specifically detects ATG4A in WB and IF. It exhibits reactivity toward Human.

Quick Overview for ATG4A antibody (AA 289-398) (ABIN3023409)

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ATG4A Antibody

Binding Specificity: AA 289-398

Sequence: TEENGTVNDQ TFHCLQSPQR MNILNLDPSV ALGFFCKEEK DFDNWCSLVQ KEILKENLRM FELVQKHPSH WPPFVPPAKP EVTTTGAEFI DSTEQLEEFD LEEDFEILSV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-398 of human ATG4A (NP_443168.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG4A

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Alternative Name: ATG4A

Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.,ATG4A,APG4A,AUTL2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Extracellular Matrix,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Cardiovascular,Heart,ATGs,ATG4A

Molecular Weight: 36 kDa/38 kDa/42 kDa/45 kDa

Gene ID: 115201

UniProt: Q8WYN0

Pathways: Autophagy